年龄、运动功能障碍和神经精神症状影响多发性硬化症患者的生活质量。
Age, motor dysfunction and neuropsychiatric symptoms impact quality of life in multiple sclerosis.
机构信息
Universidade Federal de Mato Grosso do Sul. Campo Grande, Mato Grosso do Sul, Brazil.
APAE de Campo Grande, Centro Especializado de Reabilitação. Campo Grande, Mato Grosso do Sul, Brazil.
出版信息
Rev Bras Enferm. 2022 Jun 6;75(6):e20210207. doi: 10.1590/0034-7167-2021-0207. eCollection 2022.
OBJECTIVES
to investigate the impact of age, motor dysfunction and neuropsychiatric symptoms on the quality of life of people with multiple sclerosis in comparison to healthy peers.
METHODS
a total of 141 participants were tested in a single session. The assessments were composed by general questionnaires applied in both groups and by specific instruments restricted to multiple sclerosis. Multiple regression models were applied to assess relationships between predictors and outcome.
RESULTS
age, motor dysfunction and neuropsychiatric symptoms explained 56.6% of quality of life of the multiple sclerosis group. Age and neuropsychiatric symptoms explained 36.6% of quality of life in the control group. Age impacted more the multiple sclerosis group than the control group. Neuropsychiatric symptoms affected both groups similarly. Motor dysfunction impacted 21.9% of the quality of life in multiple sclerosis.
CONCLUSIONS
the predictors explained considerable variance of quality of life in multiple sclerosis, which should guide public health policies.
目的
调查年龄、运动功能障碍和神经精神症状对多发性硬化症患者生活质量的影响，并与健康同龄人进行比较。
方法
在一次就诊中对 141 名参与者进行了测试。评估包括两组通用问卷和多发性硬化症专用特定工具。应用多元回归模型评估预测因素与结果之间的关系。
结果
年龄、运动功能障碍和神经精神症状解释了多发性硬化症组生活质量的 56.6%。年龄和神经精神症状解释了对照组生活质量的 36.6%。年龄对多发性硬化症组的影响大于对照组。神经精神症状对两组的影响相似。运动功能障碍对多发性硬化症的生活质量影响了 21.9%。
结论
预测因素解释了多发性硬化症患者生活质量的相当大的差异，这应指导公共卫生政策。
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