Olic J-Jacqueline, Stöllberger Claudia, Schukro Christoph, Odening Katja E, Reuschel Edith, Fischer Marcus, Veltmann Christian, Duncker David, Baessler Andrea
Department of Cardiology, University Hospital of Regensburg, Regensburg, Germany.
Department of Cardiology, Hospital Rudolfstiftung, Vienna, Austria.
Int J Cardiol Heart Vasc. 2022 Jun 3;41:101066. doi: 10.1016/j.ijcha.2022.101066. eCollection 2022 Aug.
Pregnancy can trigger or aggravate the risk for life-threating arrhythmias in cardiac diseases. Pregnancy is associated with reluctance for implantable cardioverter-defibrillators (ICD) due to concerns about radiation. Thus, the wearable cardioverter-defibrillator (WCD) might be an option during pregnancy. Aim of the study was to collect experiences about the use of WCD in pregnancy.
This study retrospectively included eight women who received a WCD during pregnancy. They suffered from ventricular tachycardia (VT) without known cardiac disease (n = 3), Brugada syndrome (n = 1), hypertrophic cardiomyopathy (n = 1), dilated cardiomyopathy (n = 1), non-compaction (n = 1), and survived sudden cardiac arrest during a preceding pregnancy (n = 1). WCD usage was started between 13 and 28 weeks of gestation. WCD wearing period ranged from 3 days to 30.9 weeks, WCD wearing time ranged from 13.0 to 23.7 h per day. Two women (25%) abandoned WCD already during pregnancy. Neither appropriate nor inappropriate WCD shocks were recorded. Antiarrhythmic management included beta-blockers (n = 5) and flecainide (n = 2). After delivery, ICD were implanted (n = 4), refused (n = 2) and estimated not necessary after successful catheter ablation (n = 2).
Uneventful pregnancy is possible in women at risk for sudden cardiac death by interdisciplinary monitoring and diligent pharmacotherapy protected by the WCD. Since no WCD shocks were recorded, the effectiveness of WCD during pregnancy is still unclear. However, arrhythmia detection by WCD was very good despite the changed anatomy in pregnancy. Nevertheless, further studies are necessary to assess effectiveness of WCD in pregnant women. Furthermore, efforts should be made to increase the wearing adherence of WCD during pregnancy.
妊娠可引发或加重心脏病患者出现危及生命的心律失常的风险。由于对辐射的担忧,妊娠与植入式心律转复除颤器(ICD)的使用存在顾虑。因此,可穿戴式心律转复除颤器(WCD)可能是孕期的一种选择。本研究的目的是收集关于孕期使用WCD的经验。
本研究回顾性纳入了8名在孕期接受WCD的女性。她们患有室性心动过速(VT),其中无已知心脏病的有3例,Brugada综合征1例,肥厚型心肌病1例,扩张型心肌病1例,心肌致密化不全1例,还有1例曾在前次妊娠期间发生心脏骤停并存活。WCD在妊娠13至28周开始使用。WCD佩戴期为3天至30.9周,每天佩戴时间为13.0至23.7小时。两名女性(25%)在孕期就已停用WCD。未记录到合适或不合适的WCD电击。抗心律失常治疗包括β受体阻滞剂(5例)和氟卡尼(2例)。分娩后,4例植入了ICD,2例拒绝植入,2例在成功进行导管消融后认为无需植入。
通过跨学科监测和在WCD保护下进行精心药物治疗,有心脏性猝死风险的女性有可能实现平稳妊娠。由于未记录到WCD电击,WCD在孕期的有效性仍不明确。然而,尽管孕期解剖结构发生了变化,WCD对心律失常的检测效果仍非常好。尽管如此,仍需要进一步研究来评估WCD在孕妇中的有效性。此外,应努力提高孕期WCD的佩戴依从性。