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横纹肌溶解症作为减肥手术的一种罕见并发症。

Rhabdomyolysis as a rare complication of bariatric surgery.

作者信息

Usta Sertaç, Karabulut Koray

机构信息

Department of General Surgery, Fırat University Faculty of Medicine, Elazığ, Turkey.

出版信息

Turk J Surg. 2021 Dec 31;37(4):400-402. doi: 10.47717/turkjsurg.2021.3990. eCollection 2021 Dec.

Abstract

Rhabdomyolysis after bariatric surgery is a quite rare occurrence with low recognition. Due to the breakdown of striated muscle fibers, creatine kinase and myoglobin are released into systemic circulation with variable effects on renal filtering functions. Herein, it was aimed to present a patient who de- veloped rhabdomyolysis following revision bariatric surgery. This 34-year-old male patient was admitted for bariatric surgery. He had had a gastric band surgery approximately six years ago, with regain of weight starting one year after surgery gradually reaching the previous weight level. Consequently, the gastric band had been removed with open surgery three years ago. The patient had a body mass index of 69 kg/m2 as well as an incisional hernia due to previous surgery. Although initially laparoscopic sleeve gastrectomy was planned, a switch to open surgery was made due to the presence of diffuse intra-abdominal adhesions and giant incisional hernia precluding laparoscopic intervention. The total duration of surgery was 420 minutes. Postoperative laboratory work-up showed elevated blood creatine kinase (25837 U/L). Upon the failure of fluid replacement and diuretics, hemodialy- sis was initiated at postoperative day 1. Despite daily sessions of hemodialysis, acidosis did not improve, his general status worsened and the patient died on postoperative day 14. Rhabdomyolysis is a severe and potentially life-threatening complication of bariatric surgery. Its severity may vary from asymptomatic elevations of creatine kinase to death. Postoperative creatine kinase levels should be routinely checked in high-risk patients as a practical and inexpensive laboratory modality for early diagnosis.

摘要

减重手术后发生横纹肌溶解症是一种极为罕见且认知度较低的情况。由于横纹肌纤维的分解,肌酸激酶和肌红蛋白释放到体循环中,对肾脏过滤功能产生不同程度的影响。本文旨在介绍一例在减重手术翻修术后发生横纹肌溶解症的患者。这位34岁的男性患者因减重手术入院。他大约六年前接受了胃束带手术,术后一年开始体重反弹,逐渐恢复到术前体重水平。因此,三年前通过开放手术移除了胃束带。该患者体重指数为69kg/m²,且因先前手术存在切口疝。尽管最初计划进行腹腔镜袖状胃切除术,但由于存在广泛的腹腔内粘连和巨大切口疝,无法进行腹腔镜干预,故改为开放手术。手术总时长为420分钟。术后实验室检查显示血肌酸激酶升高(25837U/L)。在补液和利尿剂治疗无效后,术后第1天开始进行血液透析。尽管每天进行血液透析,但酸中毒并未改善,患者一般状况恶化,于术后第14天死亡。横纹肌溶解症是减重手术的一种严重且可能危及生命的并发症。其严重程度可能从肌酸激酶无症状升高到死亡不等。对于高危患者,术后应常规检查肌酸激酶水平,作为早期诊断的一种实用且经济的实验室检查方法。

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