Department of Radiology, NYU Langone Health, 660 1st Avenue, New York, NY, 10016, USA.
Department of Radiology, Mayo Clinic, 200 First St, Rochester, MN, 55902, USA.
Abdom Radiol (NY). 2022 Jul;47(7):2335-2346. doi: 10.1007/s00261-022-03559-5. Epub 2022 Jun 9.
Anastomosing hemangioma (AH) is a rare, benign vascular neoplasm with distinctive histopathology and characteristic tumor distribution. AHs show marked proclivity to involve the kidneys, gonads and the retroperitoneal soft tissues; kidney is the most common target site often in the context of end stage renal disease. Recent studies have identified activating mutations of GNA genes that drive the molecular pathogenesis of AHs. AH appears as a solitary, well-circumscribed, hypervascular tumor that charters a benign course with an excellent prognosis. The purpose of this article is to provide a current update on clinical, pathological and imaging features of anastomotic hemangioma.
吻合性血管瘤（AH）是一种罕见的良性血管肿瘤，具有独特的组织病理学和特征性的肿瘤分布。AHs 明显倾向于累及肾脏、性腺和腹膜后软组织；肾脏是最常见的靶器官，常发生于终末期肾病。最近的研究已经确定了 GNA 基因的激活突变，这些突变驱动了 AHs 的分子发病机制。AH 表现为单发的、边界清楚的、富血管的肿瘤，具有良性病程和极好的预后。本文的目的是提供吻合性血管瘤的临床、病理和影像学特征的最新进展。
