Department of Epidemiology and Health Statistics, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Int J Environ Res Public Health. 2022 May 31;19(11):6740. doi: 10.3390/ijerph19116740.
The purpose of this study was to determine whether neck circumference (NC) is associated with subclinical atherosclerosis among Chinese steelworkers in North China. A cross-sectional survey was conducted among steelworkers in northern China (n = 3467). Carotid intima-media thickness (CIMT) was measured at the distal wall of the common carotid artery proximal to the bifurcation point along a plaque-free segment 10 mm long on each side by B-ultrasound. The mean of the common CIMT was used bilaterally in this study. In the cross-sectional analysis, large NC was associated with the presence of abnormal CIMT. Logistic regression analysis was used to assess the relationship between NC tertiles and CIMT. The multivariable-adjusted odds ratio was 1.76 (95% CI: 1.40 to 2.22; p for trend <0.001) for the highest tertile versus the lowest tertile and was 1.07 (95% CI: 1.04 to 1.10; p < 0.001) per 1 standard deviation increment in NC. Among steelworkers in North China, relatively large NC level is associated with elevated odds of subclinical atherosclerosis.
本研究旨在探讨颈围(NC)与中国北方钢铁工人亚临床动脉粥样硬化的相关性。本研究采用横断面调查方法,对中国北方的钢铁工人(n=3467)进行了研究。通过 B 超测量双侧颈总动脉分叉前 10mm 无斑块段的远侧壁的颈动脉内膜中层厚度(CIMT)。本研究双侧采用 CIMT 的平均值。在横断面分析中,大颈围与异常 CIMT 的存在相关。采用 logistic 回归分析评估颈围三分位与 CIMT 之间的关系。最高三分位与最低三分位相比,多变量调整后的比值比为 1.76(95%CI:1.40-2.22;趋势 p<0.001),NC 每增加 1 个标准差,比值比为 1.07(95%CI:1.04-1.10;p<0.001)。在中国北方的钢铁工人中,较大的颈围水平与亚临床动脉粥样硬化的患病风险升高相关。