Hayakawa Azusa, Tsukahara Kengo, Miyagawa Shuichi, Okajima Yuichi, Takano Keiko, Mitsuhashi Takayuki, Maejima Nobuhiko, Kosuge Masami, Tamura Kouichi, Kimura Kazuo
Division of Cardiology, Fujisawa City Hospital, Fujisawa City, Japan.
Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
J Cardiol Cases. 2022 Feb 20;25(6):404-407. doi: 10.1016/j.jccase.2022.01.006. eCollection 2022 Jun.
A 78-year-old man suffering from epigastric discomfort presented with an initial electrocardiogram showing complete right bundle branch block (RBBB) and ST-segment depression continuing to positive symmetrical T waves in leads V2 to V4, suggestive of de Winter's pattern. Emergent coronary angiography demonstrated 2-vessel disease with 90% stenosis in the proximal segment of the left anterior descending artery (LAD) with Thrombolysis in Myocardial Infarction (TIMI) grade 3 flow, and 75% in the mid portion and 90% in the distal portion of the right coronary artery, without collateral flow to LAD. A drug-eluting stent was deployed at the proximal LAD, and the flow of the diagonal branch deteriorated to TIMI grade 1 flow on the final angiogram. De Winter's pattern temporarily disappeared, and the procedure was finished. However, when the patient was admitted to the coronary care unit, de Winter's pattern emerged again with less severe epigastric discomfort. Subsequently, chest X-ray showed pulmonary edema in both lungs. Repeat angiography revealed acute stent thrombosis of LAD with TIMI grade 1 flow. De Winter's pattern with the combination of RBBB can be observed not only on admission but also at the time of occurrence of stent thrombosis. < De Winter's pattern reflects thrombotic occlusion of a large coronary artery without ST-segment elevation, and can be observed not only on admission but also at the time of occurrence of stent thrombosis. Positive T waves of de Winter's pattern in the right to mid precordial leads suggest acute thrombotic occlusion of left anterior descending artery, even in the presence of right bundle branch block.>.
一名78岁患有上腹部不适的男性,其初始心电图显示完全性右束支传导阻滞(RBBB),V2至V4导联ST段压低并延续至正向对称T波,提示为de Winter's图形。急诊冠状动脉造影显示双支血管病变,左前降支(LAD)近端狭窄90%,心肌梗死溶栓治疗(TIMI)血流3级,右冠状动脉中段狭窄75%,远端狭窄90%,无向LAD的侧支血流。在LAD近端植入药物洗脱支架,最终血管造影显示对角支血流恶化为TIMI 1级血流。de Winter's图形暂时消失,手术结束。然而,当患者入住冠心病监护病房时,de Winter's图形再次出现,上腹部不适较轻。随后,胸部X线显示双肺肺水肿。重复血管造影显示LAD急性支架血栓形成,TIMI 1级血流。不仅在入院时,而且在支架血栓形成时,均可观察到de Winter's图形与RBBB的组合。<de Winter's图形反映了无ST段抬高的大冠状动脉血栓性闭塞,不仅在入院时,而且在支架血栓形成时均可观察到。右胸前导联至胸前中部导联de Winter's图形的正向T波提示左前降支急性血栓性闭塞,即使存在右束支传导阻滞。>