脂肪移植的安全性：机构回顾性研究。

The Safety of Fat Grafting: An Institutional Retrospective Review.

机构信息

From the University of Alabama in Birmingham School of Medicine.

Division of Plastic Surgery, University of Alabama in Birmingham, Birmingham, AL.

出版信息

Ann Plast Surg. 2022 Jun 1;88(5 Suppl 5):S473-S477. doi: 10.1097/SAP.0000000000003234.

DOI:10.1097/SAP.0000000000003234

PMID:35690941

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9893916/

Abstract

BACKGROUND

Autologous fat grafting is a popular technique for volume replacement in the breast and face. The efficacy, safety, and complication rate of this technique at the division of plastic surgery at the University of Alabama at Birmingham will be described in this review.

METHODS

An institutional review board-approved retrospective review of patients undergoing fat grafting procedures from January 2015 to July 2018 was performed. Records were reviewed for fat graft recipient site, donor site, amount grafted, and complications. Continuous variables were compared using either a t test or one-way analysis of variance test. Categorical data were compared using χ2 test. A P value of 0.05 or less was considered statistically significant for all comparisons.

RESULTS

A total of 396 patients who underwent fat grafting procedures of the face and body from January 2015 through July 2018 met inclusion criteria. Average amount of fat grafted for all grafts was 124.4 +/- 6.74 grams. Two hundred fifty of the grafts (62.7%) involved the bilateral breasts with an average of 140.6 +/- 93.97 g used, 70 per side. Of the 396 patients, 110 (27.8%) experienced complications. Forty three of the complications (10.9%) were considered to be major, which included hematomas/seromas, fat necrosis, dermatitis/cellulitis, and infection. No statistical differences were seen among recipient site complication rate. Types of minor complications were statistically significant per recipient sites with bilateral breasts more likely to experience asymmetry than the other recipient sites (20% for bilateral breasts vs 16% overall, P < 0.05). Fifty nine of the 110 patients (53.6%) had the complications reported to be resolved.

CONCLUSIONS

Fat grafting is a reliable method for volumization of the breasts and face. Minor complications were not infrequent in this case series; however, no life-threatening complications were observed. Continued work needs to be done to use fat grafting beyond traditional measures.

摘要

背景

自体脂肪移植是一种在乳房和面部进行体积置换的常用技术。本研究将描述阿拉巴马大学伯明翰分校整形外科学分部使用该技术的疗效、安全性和并发症发生率。

方法

对 2015 年 1 月至 2018 年 7 月期间接受脂肪移植手术的患者进行机构审查委员会批准的回顾性研究。对脂肪移植物受区、供区、移植量和并发症的记录进行了回顾。连续变量比较采用 t 检验或单因素方差分析。分类数据采用卡方检验。所有比较均以 P 值<0.05 为差异有统计学意义。

结果

2015 年 1 月至 2018 年 7 月期间，共有 396 例接受面部和身体脂肪移植的患者符合纳入标准。所有移植的平均脂肪量为 124.4±6.74 克。250 例（62.7%）移植涉及双侧乳房，平均每侧使用 140.6±93.97 克。396 例患者中，110 例（27.8%）出现并发症。其中 43 例（10.9%）为严重并发症，包括血肿/血清肿、脂肪坏死、皮炎/蜂窝织炎和感染。各受区并发症发生率无统计学差异。各受区的轻微并发症类型有统计学意义，双侧乳房更易出现不对称（双侧乳房 20%，总体 16%，P<0.05）。110 例患者中有 59 例（53.6%）报告并发症已解决。