Suppr超能文献

功能能力、肌肉减少症与骨骼健康。

Functional capacity, sarcopenia, and bone health.

作者信息

Laskou Faidra, Patel Harnish, Cooper Cyrus, Dennison Elaine

机构信息

MRC Lifecourse Epidemiology Centre, Southampton, SO16 6YD, UK, USA.

出版信息

Best Pract Res Clin Rheumatol. 2022 Sep;36(3):101756. doi: 10.1016/j.berh.2022.101756. Epub 2022 Jun 10.

Abstract

Bone and muscle are recognised as interacting tissues, the so-called 'muscle-bone unit', in which these two tissues communicate to coordinate their development (chemically and metabolically), as well as their response to loading or injury. Musculoskeletal disorders of ageing, specifically osteoporosis and sarcopenia, are highly prevalent in older individuals. They signify a significant burden for older people affecting their mobility, confidence, and quality of life, as well as being a major cost to healthcare systems worldwide. This review considers the coexistence of osteoporosis and sarcopenia in individuals and describes risk factors, clinical consequences, approaches to management, and the link with functional capacity.

摘要

骨骼和肌肉被认为是相互作用的组织,即所谓的“肌肉-骨骼单元”,在这个单元中,这两种组织相互交流,以协调它们的发育(化学和代谢方面),以及它们对负荷或损伤的反应。衰老引起的肌肉骨骼疾病,特别是骨质疏松症和肌肉减少症,在老年人中非常普遍。它们给老年人带来了巨大负担,影响他们的行动能力、自信心和生活质量,同时也是全球医疗保健系统的一项重大成本。本综述探讨了个体中骨质疏松症和肌肉减少症的共存情况,并描述了风险因素、临床后果、管理方法以及与功能能力的联系。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验