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血管内治疗在肺癌患者电视辅助胸腔镜肺叶切除术后急性缺血性脑卒中的应用:四例报告并文献复习。

Endovascular Treatment for Acute Ischemic Stroke After Video-Assisted Thoracoscopic Pulmonary Lobectomy in Patients With Lung Cancer: A Report of Four Cases and Literature Review.

机构信息

Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

J Stroke Cerebrovasc Dis. 2022 Aug;31(8):106593. doi: 10.1016/j.jstrokecerebrovasdis.2022.106593. Epub 2022 Jun 10.

Abstract

BACKGROUND

Postoperative cerebral embolic stroke is a serious complication of pulmonary lobectomy, occurring in 1.1% of patients undergoing lobectomy through video-assisted thoracoscopic surgery (VATS). The mechanism of this complication is thought to be embolic stroke caused by thrombus formed due to stagnation in the pulmonary vein stump after VATS lobectomy. There have been few reports demonstrating the utility of endovascular treatment (EVT) for cerebral embolic stroke after VATS lobectomy.

CASE DESCRIPTION

In our case series, cerebral embolic stroke occurred after VATS pulmonary lobectomy for lung cancer, including the left upper lobe in three cases and the right lobe in one. The median duration of ischemic stroke after VATS was 4.5 days (interquartile range, 2-9 days). The median time from stroke onset to puncture was 130 min. Successful recanalization was achieved in all cases, and two patients achieved favorable clinical outcomes (modified Rankin scale, 0-2).

CONCLUSION

We report a case series of four patients who underwent EVT for acute embolic stroke after VATS lobectomy for lung cancer. EVT is considered a reasonable and feasible therapeutic option for this condition.

摘要

背景

术后脑栓塞是电视辅助胸腔镜手术(VATS)肺叶切除术后的一种严重并发症,发生率为 1.1%。该并发症的发生机制被认为是由于 VATS 肺叶切除术后肺静脉残端停滞导致血栓形成引起的栓塞性卒中。很少有报道证明血管内治疗(EVT)对 VATS 肺叶切除术后脑栓塞的疗效。

病例描述

在我们的病例系列中,4 例肺癌患者行 VATS 肺叶切除术后发生脑栓塞,包括左肺上叶 3 例,右肺 1 例。VATS 后缺血性卒中的中位时间为 4.5 天(四分位距,2-9 天)。从卒中发病到穿刺的中位时间为 130 分钟。所有病例均成功再通,2 例患者获得良好的临床结局(改良 Rankin 量表,0-2)。

结论

我们报告了 4 例因肺癌行 VATS 肺叶切除术后急性栓塞性卒中而行 EVT 的患者病例系列。EVT 被认为是该疾病的一种合理且可行的治疗选择。

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