Janus-faced citrate in aging and metabolism.
作者信息
Lin Wei-Sheng, Wang Pei-Yu
机构信息
Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan.
School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
出版信息
Aging (Albany NY). 2022 Jun 17;14(12):4929-4930. doi: 10.18632/aging.204138.
Abstract
摘要
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Janus-faced citrate in aging and metabolism.衰老与代谢中具有两面性的柠檬酸盐
Aging (Albany NY). 2022 Jun 17;14(12):4929-4930. doi: 10.18632/aging.204138.
2
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Inhibition of citrate oxidation by glyoxylate in rat-liver homogenates.乙醛酸对大鼠肝脏匀浆中柠檬酸氧化的抑制作用。
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7
The action of cocarboxylase on pyruvate utilisation and citrate formation in the liver of normal and diabetic rats.辅酶羧化酶对正常和糖尿病大鼠肝脏中丙酮酸利用及柠檬酸形成的作用。
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[Effect of several coenzymes on the formation of citrate in tissue homogenates of normal and diabetic rats].[几种辅酶对正常及糖尿病大鼠组织匀浆中柠檬酸形成的影响]
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本文引用的文献
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NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans.NHR-80 通过感知线粒体未折叠蛋白反应来重新布线柠檬酸代谢，以促进秀丽隐杆线虫的脂类积累。
Cell Rep. 2022 Jan 11;38(2):110206. doi: 10.1016/j.celrep.2021.110206.
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Citrate Promotes Excessive Lipid Biosynthesis and Senescence in Tumor Cells for Tumor Therapy.柠檬酸盐促进肿瘤细胞中脂质生物合成和衰老以用于肿瘤治疗。
Adv Sci (Weinh). 2022 Jan;9(1):e2101553. doi: 10.1002/advs.202101553. Epub 2021 Nov 7.
3
Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesis.饮食中补充柠檬酸盐可通过促进酮体生成来延长寿命、改善代谢健康和记忆力。
Aging Cell. 2021 Dec;20(12):e13510. doi: 10.1111/acel.13510. Epub 2021 Oct 31.
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Nervous System Deletion of Mammalian INDY in Mice Mimics Dietary Restriction-Induced Memory Enhancement.小鼠中哺乳动物INDY的神经系统缺失模拟饮食限制诱导的记忆增强。
J Gerontol A Biol Sci Med Sci. 2021 Jan 1;76(1):50-56. doi: 10.1093/gerona/glaa203.
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Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction-induced memory enhancement.5-羟色胺受体 HTR6 介导的 mTORC1 信号通路调节饮食限制诱导的记忆增强。
PLoS Biol. 2019 Mar 18;17(3):e2007097. doi: 10.1371/journal.pbio.2007097. eCollection 2019 Mar.
6
Intermittent metabolic switching, neuroplasticity and brain health.间歇性代谢转换、神经可塑性与大脑健康。
Nat Rev Neurosci. 2018 Feb;19(2):63-80. doi: 10.1038/nrn.2017.156. Epub 2018 Jan 11.
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Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.缺失哺乳动物 INDY 同源物模拟了饮食限制的某些方面，并能预防肥胖和胰岛素抵抗。
Cell Metab. 2011 Aug 3;14(2):184-95. doi: 10.1016/j.cmet.2011.06.009.
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Long-lived Indy and calorie restriction interact to extend life span.长寿基因Indy与热量限制共同作用以延长寿命。
Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9262-7. doi: 10.1073/pnas.0904115106. Epub 2009 May 22.
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