洛美他派的逐步剂量滴定可能预防纯合子家族性高胆固醇血症患者的治疗延迟。 - Suppr

Gradual dose Titration of Lomitapide may Prevent Therapeutic Delays in Patients with Homozygous Familial Hypercholesterolemia.

作者信息

Harada-Shiba Mariko, Koezuka Ryo, Makino Hisashi, Ogura Masatsune

机构信息

Department of Molecular Pathogenesis, National Cerebral and Cardiovascular Center Research Institute.

Cardiovascular Center, Osaka Medical and Pharmaceutical University.

出版信息

J Atheroscler Thromb. 2023 Feb 1;30(2):203-205. doi: 10.5551/jat.LE003. Epub 2022 Jun 23.

DOI:10.5551/jat.LE003

PMID:35732425

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9925198/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e51/9925198/0f31dbe4f1b2/30_LE003_1.jpg

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本文引用的文献

Homozygous Familial Hypercholesterolemia.

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Familial Hypercholesterolemia and Lipoprotein Apheresis.

J Atheroscler Thromb. 2019 Aug 1;26(8):679-687. doi: 10.5551/jat.RV17033. Epub 2019 Jun 22.

Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017.

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Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study.

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New approaches to target microsomal triglyceride transfer protein.

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Gradual dose Titration of Lomitapide may Prevent Therapeutic Delays in Patients with Homozygous Familial Hypercholesterolemia.

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