Li Bin, Quan Yuping, He Yufei, He Yunfan, Lu Feng, Liao Yunjun, Cai Junrong
Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Front Surg. 2022 Jun 10;9:895674. doi: 10.3389/fsurg.2022.895674. eCollection 2022.
Autologous fat transfer is common in breast augmentationor reconstruction. However, AFG recipient site in the breast for fat grafting has not been carefully investigated.
Forty female patients requiring breast augmentation with fat grafting were randomly assigned into two groups. The retromammary group received 2/3 fat into the retromammary space and the other 1/3 into the subcutaneous and retropectoral planes. The retropectoral group received 2/3 fat into the retropectoral plane and the other 1/3 into the subcutaneous and retromammary planes. The fat grafting result at 6 months was assessed by 3D laser surface scanning and then ultrasound. Any complications were recorded during follow-up. Samples from a patient who underwent fat grafting for 6 months was obtained and histological examination was conducted.
No significant difference in the retention rate after 6 months was observed between the two groups (retromammary group: 35.9% ± 6.6; retropectoral group: 39.3% ± 5.1, = 0.1076). The retromammary grouphad a higher incidence of oil cyst formation than the retropectoral group. Histological examination showed that there were more oil cysts and mac2 positive macrophage infiltration in the fat cells in retromammary group, while retropectoral group had more small-size adipocytes.
Although fat grafting into the retropectoral plane did not provide a superior fat graft retention rate, it did lower the incidence of complications. The retropectoral space show great potential to become a favorable recipient site.
自体脂肪移植在隆乳或乳房重建中很常见。然而，乳房中用于脂肪移植的受区尚未得到仔细研究。
40例需要通过脂肪移植进行隆乳的女性患者被随机分为两组。乳腺后组将2/3的脂肪注入乳腺后间隙，另外1/3注入皮下和胸肌后平面。胸肌后组将2/3的脂肪注入胸肌后平面，另外1/3注入皮下和乳腺后平面。6个月时通过三维激光表面扫描评估脂肪移植效果，然后进行超声检查。随访期间记录任何并发症。获取一名接受脂肪移植6个月患者的样本并进行组织学检查。
两组6个月后的留存率无显著差异（乳腺后组：35.9%±6.6；胸肌后组：39.3%±5.1，P = 0.1076）。乳腺后组油囊肿形成的发生率高于胸肌后组。组织学检查显示，乳腺后组脂肪细胞中有更多油囊肿和Mac2阳性巨噬细胞浸润，而胸肌后组有更多小尺寸脂肪细胞。
尽管将脂肪移植到胸肌后平面并没有提供更高的脂肪留存率，但它确实降低了并发症的发生率。胸肌后间隙显示出成为良好受区的巨大潜力。
