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[迟发性精神病中的认知功能]

[Cognitive functions in late-onset psychosis].

作者信息

Abdullina E G, Savina M A, Rupchev G E, Sheshenin V S, Pochueva V V

机构信息

Lomonosov Moscow State University, Moscow, Russia.

Mental Health Research Center, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(6):63-70. doi: 10.17116/jnevro202212206163.

Abstract

The review discusses cognitive functions in late-onset schizophrenia and very late-onset schizophrenia-like psychosis compared to cognition in normal aging, early-onset schizophrenia, and neurodegenerative diseases. The problem of the dynamics of the state of the cognitive functions in patients with late-onset schizophrenic psychoses is highlighted, and prospects for further research are discussed. Patients with late-onset schizophrenic psychosis are characterized by more pronounced cognitive deficits compared to normal aging, but less severe than cognitive changes observed in early-onset schizophrenia. Late-onset schizophrenia may be a heterogeneous condition in terms of cognitive dysfunction.

摘要

该综述讨论了晚发性精神分裂症和极晚发性精神分裂症样精神病中的认知功能,并将其与正常衰老、早发性精神分裂症和神经退行性疾病中的认知功能进行了比较。文中强调了晚发性精神分裂症性精神病患者认知功能状态的动态变化问题,并探讨了进一步研究的前景。与正常衰老相比,晚发性精神分裂症性精神病患者的特征是存在更明显的认知缺陷,但比早发性精神分裂症中观察到的认知变化要轻。就认知功能障碍而言,晚发性精神分裂症可能是一种异质性疾病。

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