可溶性ST2：心力衰竭中一种有价值的预后标志物。
Soluble ST2: a valuable prognostic marker in heart failure.
作者信息
Savarimuthu Sugeevan, Goel Pavan, Harky Amer
机构信息
Department of Medicine, Basildon Hospital, Basildon, UK.
Department of Pharmacy, Liverpool Heart and Chest Hospital, Liverpool, UK.
出版信息
Heart Fail Rev. 2022 Nov;27(6):2155-2164. doi: 10.1007/s10741-022-10258-2. Epub 2022 Jun 27.
Natriuretic peptides have been at the forefront of biomarker use in heart disease and have been universally recommended as the ideal biomarker in the setting of heart failure. Soluble ST2 is one such biomarker which has found value as a prognostic marker and can be used individually or along with natriuretic peptides in order to prognosticate patients with heart failure. Leading cardiovascular organisations have recognised this biomarker, though its role as a diagnostic marker is yet to be determined. We aim to investigate the role of sST2 in heart failure in the existing literature.
利钠肽一直处于心脏病生物标志物应用的前沿，并被普遍推荐为心力衰竭情况下的理想生物标志物。可溶性ST2就是这样一种生物标志物，它已被证明具有预后标志物的价值，可单独使用或与利钠肽一起用于预测心力衰竭患者的预后。主要的心血管组织已经认可了这种生物标志物，尽管其作为诊断标志物的作用尚未确定。我们旨在研究现有文献中sST2在心力衰竭中的作用。
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