Huang Bin-Bin, Niu Shi-Kun
Department of Surgical Anesthesia, Shiyan Maternal and Child Health Hospital, Shiyan, China.
Evid Based Complement Alternat Med. 2022 Jun 21;2022:4447484. doi: 10.1155/2022/4447484. eCollection 2022.
: To study the effects of epidural anesthesia with different doses of dexmedetomidine and ropivacaine on postoperative hemodynamics and neonatal outcome of cesarean section parturients. . A total of 90 parturients who underwent cesarean section admitted to our hospital from January 2019 to January 2020 were selected as the research objects and were divided into groups A, B, and C according to different dosages of dexmedetomidine, with 30 cases in each group. Groups A, B, and C were given dexmedetomidine 0.5 g/kg, 0.8 g/kg, 1.0 g/kg, respectively, combined with 0.2% ropivacaine. The anesthesia effect, traction response, hemodynamic indexes, and neonatal Apgar score of the three groups were compared; the "Numerical Rating Scale (NRS) Score" was used to assess the postoperative pain of the parturients, and the "Ramsay Sedation Scale" was used to assess the sedation state of the parturients. . The superior anesthesia effect of group B was obtained compared with groups A and C ( < 0.05). Group B witnessed a lower degree of grade III stretching response, as compared to group A ( < 0.05). In comparison with groups A and C, superior results of the heart rate and mean artery pressure (MAP) of group B at T1 and T2 were obtained ( < 0.05). The neonatal Apgar score in group B was lower than those in groups A and C ( < 0.05), and the NRS score of group B was also lower than that of group A ( < 0.05). Compared with groups A and C, group B yielded a more favorable outcome in terms of the Ramsay score ( < 0.05). . The use of medium-dose dexmedetomidine in cesarean section parturients is safer and can effectively reduce the impact on maternal hemodynamics, which is worthy of promotion and application.
研究不同剂量右美托咪定与罗哌卡因硬膜外麻醉对剖宫产产妇术后血流动力学及新生儿结局的影响。选取2019年1月至2020年1月我院收治的90例行剖宫产的产妇作为研究对象，根据右美托咪定不同剂量分为A、B、C组，每组30例。A、B、C组分别给予右美托咪定0.5μg/kg、0.8μg/kg、1.0μg/kg，联合0.2%罗哌卡因。比较三组的麻醉效果、牵拉反应、血流动力学指标及新生儿Apgar评分；采用“数字评分法（NRS）评分”评估产妇术后疼痛情况，采用“Ramsay镇静评分”评估产妇镇静状态。与A、C组比较，B组麻醉效果更佳（P<0.05）。与A组比较，B组Ⅲ级牵拉反应程度更低（P<0.05）。与A、C组比较，B组在T1、T2时心率及平均动脉压（MAP）结果更优（P<0.05）。B组新生儿Apgar评分低于A、C组（P<0.05），B组NRS评分也低于A组（P<0.05）。与A、C组比较，B组Ramsay评分结果更优（P<0.05）。剖宫产产妇使用中剂量右美托咪定更安全，能有效减轻对产妇血流动力学的影响，值得推广应用。
