Department of Anesthesiology, University Hospital Leuven.
Department of Abdominal Surgery, University Hospital Leuven.
Acta Chir Belg. 2023 Aug;123(4):440-443. doi: 10.1080/00015458.2022.2040108. Epub 2022 Jun 30.
In this case report we describe a 38-year old female patient admitted to the emergency department with acute abdomen and sepsis. Broad-spectrum antibiotics were started. Abdominal imaging was inconclusive, exploratory laparoscopy showed four-quadrant peritonitis. No provoking factor could be withheld. Due to clinical deterioration the patient was transferred to the intensive care unit. Blood cultures showed the presence of group A streptococcus, and clindamycin was associated. She recovered, and could be discharged after several days. Peritonitis caused by group A is rare in healthy individuals, and occurs mostly in middle-aged women. There is no consensus regarding surgical treatment but surgical exploration is often necessary to exclude secondary peritonitis. Treatment with broad-spectrum antibiotics and supportive measurements remain the cornerstone in patient management. Association of clindamycin has been shown to reduce mortality. There is inconclusive evidence to support Intravenous polyspecific immunoglobulin G (IVIG) therapy in streptococcal toxic shock syndrome.
在本病例报告中,我们描述了一位 38 岁女性患者因急性腹痛和脓毒症入住急诊科。开始使用广谱抗生素。腹部影像学检查结果不确定,腹腔镜探查显示四象限腹膜炎。未发现诱发因素。由于病情恶化,患者被转至重症监护病房。血培养显示存在 A 组链球菌,并联合使用克林霉素。她康复了,几天后可以出院。健康个体中由 A 组链球菌引起的腹膜炎很少见,主要发生在中年女性。关于手术治疗尚无共识,但为了排除继发性腹膜炎,通常需要进行手术探查。广谱抗生素和支持性治疗仍然是患者管理的基石。联合使用克林霉素已被证明可降低死亡率。尚无确凿证据支持在链球菌中毒性休克综合征中使用静脉注射多特异性免疫球蛋白 G(IVIG)治疗。