Faculty of medicine, Zagazig University, Egypt.
Faculty of medicine, Zagazig University, Egypt.
Tissue Cell. 2022 Aug;77:101857. doi: 10.1016/j.tice.2022.101857. Epub 2022 Jun 20.
Acute myocardial infarction (AMI) is a condition with myocardial necrosis caused by an unstable ischemic syndrome. AMI is the leading cause of disability and death around the world. Extracellular vesicles (EVs) are small-sized fragments of phospholipids produced by the outward budding of the cell membrane of different types of cells (red blood cells, endothelial cells, platelets, and leukocytes). EVs are released in healthy individuals and patients with various diseases and health conditions. EVs can be detected in all biological fluids such as plasma, urine, and CSF. In this article, we attempt to answer the question, "Can circulating extracellular vesicles be used as potential biomarkers in AMI?".
急性心肌梗死（AMI）是一种由不稳定缺血综合征引起的心肌坏死疾病。AMI 是全球范围内导致残疾和死亡的主要原因。细胞外囊泡（EVs）是由不同类型细胞（红细胞、内皮细胞、血小板和白细胞）的细胞膜向外出芽产生的小型磷脂碎片。EVs 在健康个体和患有各种疾病及健康状况的患者中都会释放。EVs 可以在所有生物体液中检测到，如血浆、尿液和 CSF。在本文中，我们试图回答“循环细胞外囊泡是否可作为 AMI 的潜在生物标志物？”这一问题。
