一项确定足部和踝关节骨与软组织肿瘤发病率及分布模式的研究。

A Study to Determine the Incidence and Distribution Patterns of Foot and Ankle Tumors in Bone and Soft Tissue.

作者信息

Karadeniz Selami, Yurtbay Alparslan, Albayrak Bedirhan, Büyükceran İsmail, Dabak Nevzat

机构信息

Orthopedics and Traumatology, Amasya University, Amasya, TUR.

Orthopedics and Traumatology, Samsun Education and Research Hospital, Samsun, TUR.

出版信息

Cureus. 2022 Jun 2;14(6):e25598. doi: 10.7759/cureus.25598. eCollection 2022 Jun.

DOI:10.7759/cureus.25598

PMID:35784979

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9249027/

Abstract

OBJECTIVES

The aim of this study is to determine the incidence and distribution patterns of foot and ankle tumors in bone and soft tissue in a university tumor institute, to help the correct evaluation of uncertain masses, to take the right steps in advanced diagnosis and treatment, and to contribute to future research.

MATERIALS AND METHODS

A retrospective analysis of a total of 164 foot and ankle cases examined by a multidisciplinary bone and soft-tissue tumors care team between January 2004 and December 2021 was performed from a database in which patient information was recorded in our tertiary university hospital. Thirty-three (20.1%) of 164 patients were discussed in the tumor council and evaluated as having the non-tumor disease. All of these patients were excluded from the study. A total of 131 patients diagnosed with tumors were included in this study.

RESULTS

The lesion was determined as a benign tumor in 84 (64.1%) cases of 131 tumor patients included in the study. Of these 84 patients, 40 (47.6%) were identified as benign bone lesions and 44 (52.4%) as benign soft-tissue lesions. Malignancy was determined in 47 (35.9%) of 131 patients, affecting the bone in 14 (29.8%) patients and the soft tissue in 33 (70.2%). The malignant soft-tissue lesion most determined was malignant mesenchymal tumor in 10 (30.3%) patients, of which one had lung metastasis and one was determined with multiple metastases. Metastasis was detected in eight patients in total, including three metastatic malignant bone tumors and five metastatic malignant soft-tissue tumors.

CONCLUSIONS

Tumors involving the foot and ankle are not frequently encountered, and most tumors in this region are benign. The anatomic structure of the foot allows early diagnosis, but for diagnosis to be made, there must first be clinical suspicion. The first symptom is generally swelling. Early diagnosis can prevent several complications. Therefore, patients with foot and ankle complaints must be taken seriously and evaluated with advanced tests if necessary.

摘要

目的

本研究旨在确定某大学肿瘤研究所中骨与软组织的足踝部肿瘤的发病率及分布模式，以帮助正确评估不明肿物，在晚期诊断和治疗中采取正确措施，并为未来研究提供参考。

材料与方法

对2004年1月至2021年12月期间由多学科骨与软组织肿瘤护理团队检查的总共164例足踝病例进行回顾性分析，数据来自我们三级大学医院记录患者信息的数据库。164例患者中有33例（20.1%）在肿瘤委员会进行了讨论，并被评估为患有非肿瘤性疾病。所有这些患者均被排除在研究之外。本研究共纳入131例被诊断为肿瘤的患者。

结果

在纳入研究的131例肿瘤患者中，84例（64.1%）的病变被确定为良性肿瘤。在这84例患者中，40例（47.6%）被确定为良性骨病变，44例（52.4%）为良性软组织病变。131例患者中有47例（35.9%）被确定为恶性，其中14例（29.8%）累及骨，33例（70.2%）累及软组织。最常见的恶性软组织病变是恶性间叶性肿瘤，共10例（30.3%），其中1例有肺转移，1例有多处转移。总共8例患者检测到转移，包括3例转移性恶性骨肿瘤和5例转移性恶性软组织肿瘤。