Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine.
Circ J. 2022 Jul 25;86(8):1229-1236. doi: 10.1253/circj.CJ-22-0162. Epub 2022 Jul 1.
Pulmonary vein (PV) stenosis after atrial fibrillation (AF) ablation is rare; however, it remains a serious complication. PV angioplasty is reportedly an effective therapy; however, a dedicated device for PV angioplasty has not been developed, and the detailed procedural methods remain undetermined. This study describes the symptoms, indications, treatment strategies, and long-term outcomes for PV stenosis after AF ablation.
This study retrospectively analyzed 7 patients with PV stenosis after catheter ablation for AF and who had undergone PV angioplasty at our hospital during 2015-2021. PV stenosis occurred in the left superior (5 patients) and left inferior (2 patients) PV. Six patients had hemoptysis, chest pain, and dyspnea. Seven de novo lesions were treated using balloon angioplasty (BA) (3 patients), a bare metal stent (BMS) (3 patients), and a drug-coated balloon (DCB) (1 patient). The restenosis rate was 42.9% (n=3; 2 patients in the BA group and 1 patient in the DCB group). The repeat treatment rate was 28.6% (2 patients in the BA group). Stenting was performed as repeat treatment. One patient with subsequent repeat restenosis development underwent BA. Ten PV angioplasties were performed; there were no major complications.
Regarding PV angioplasty after ablation therapy for AF, stenting showed superior long-term PV patency than BA alone; therefore, it should be considered as a standard first-line approach.
房颤(AF)消融术后肺静脉(PV)狭窄较为少见,但仍是一种严重的并发症。据报道,PV 成形术是一种有效的治疗方法;然而,尚未开发出专门用于 PV 成形术的设备,其详细的手术方法仍不确定。本研究描述了 AF 消融术后 PV 狭窄的症状、适应证、治疗策略和长期预后。
本研究回顾性分析了 2015 年至 2021 年期间在我院行 PV 成形术治疗 AF 消融术后 PV 狭窄的 7 例患者。PV 狭窄发生在左优势(5 例)和左下(2 例)PV。6 例患者出现咯血、胸痛和呼吸困难。7 例新发病变采用球囊血管成形术(BA)(3 例)、裸金属支架(BMS)(3 例)和药物涂层球囊(DCB)(1 例)治疗。再狭窄率为 42.9%(n=3;BA 组 2 例,DCB 组 1 例)。重复治疗率为 28.6%(BA 组 2 例)。支架置入作为重复治疗。1 例随后再次发生再狭窄的患者接受了 BA。共进行了 10 次 PV 成形术,无重大并发症发生。
对于 AF 消融治疗后的 PV 成形术,支架置入术在长期 PV 通畅性方面优于单纯 BA,因此应考虑作为标准的一线治疗方法。