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针对英格兰北部贫困社区初级保健中降低心血管疾病风险管理不平等的血脂管理干预措施的定制:一项混合方法干预措施开发方案。

Tailoring lipid management interventions to reduce inequalities in cardiovascular disease risk management in primary care for deprived communities in Northern England: a mixed-methods intervention development protocol.

机构信息

Faculty of Medical Sciences, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK

NIHR Applied Research Collaborative North East and North Cumbria, Cumbria, Northumberland and Tyne and Wear NHS Foundation Trust, Newcastle upto Tyne, UK.

出版信息

BMJ Open. 2022 Jul 4;12(7):e058951. doi: 10.1136/bmjopen-2021-058951.

Abstract

INTRODUCTION

Hyperlipidaemia contributes a significant proportion of modifiable cardiovascular disease (CVD) risk, which is a condition that disproportionally affects disadvantaged socioeconomic communities, with death rates in the most deprived areas being four times higher than those in the least deprived. With the national CVD Prevention programme being delivered to minimise risk factors, no evidence is available on what has been implemented in primary care for deprived populations. This study describes the protocol for the development of a tailored intervention aiming to optimise lipid management in primary care settings to help reduce inequalities in CVD risks and improve outcomes in deprived communities.

METHODS AND ANALYSIS

A mixed-methods approach will be employed consisting of four work packages: (1) rapid review and logic model; (2) assessment and comparison of CVD risk management for deprived with non-deprived populations in Northern England to England overall; (3) interviews with health professionals; and (4) intervention development. A systematic search and narrative synthesis will be undertaken to identify evidence-based interventions and targeted outcomes in deprived areas. General practice-level data will be assessed to establish the profile of lipid management, compared with the regional and national levels. Health professionals involved in the organisation and delivery of routine lipid management to deprived populations will be interviewed to understand the implementation and delivery of current lipid management and associated challenges. The prototype intervention will be informed by the evidence generated from workpackages 1-3, which will be reviewed and assessed using the nominal group technique to reach consensus. Training and skills development materials will also be developed as needed.

ETHICS AND DISSEMINATION

Ethics approval has been obtained from the Faculty of Medical Sciences Research Ethics Committee at Newcastle University, UK. Findings will be disseminated to the participating sites, participants, commissioners, and in peer-reviewed journals and academic conferences.

摘要

简介

高脂血症是可改变的心血管疾病(CVD)风险的重要组成部分,这种情况不成比例地影响到处于不利社会经济地位的社区,最贫困地区的死亡率是最富裕地区的四倍。由于正在实施国家 CVD 预防计划来降低风险因素,但在初级保健中针对贫困人群实施了哪些措施尚无证据。本研究描述了开发针对在初级保健环境中优化脂质管理的定制干预措施的方案,以帮助减少 CVD 风险的不平等,并改善贫困社区的结果。

方法和分析

采用混合方法,包括四个工作包:(1)快速审查和逻辑模型;(2)评估和比较英格兰北部贫困人群与非贫困人群的 CVD 风险管理与英格兰整体情况;(3)与卫生专业人员进行访谈;(4)干预措施的制定。将进行系统搜索和叙述性综合,以确定贫困地区的循证干预措施和针对性结果。将评估一般实践水平的数据,以确定脂质管理的概况,并与区域和国家水平进行比较。将对参与为贫困人群组织和提供常规脂质管理的卫生专业人员进行访谈,以了解当前脂质管理的实施和提供情况以及相关挑战。将根据工作包 1-3 生成的证据来制定原型干预措施,并使用名义小组技术进行审查和评估,以达成共识。根据需要还将开发培训和技能发展材料。

伦理和传播

英国纽卡斯尔大学医学科学研究伦理委员会已批准该伦理。研究结果将在参与的地点、参与者、决策者以及同行评议期刊和学术会议上进行传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b9a/9255393/790241b9ae47/bmjopen-2021-058951f01.jpg

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