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用于人体呼吸监测的柔性、高灵敏度纸质丝网印刷多壁碳纳米管/聚二甲基硅氧烷复合呼吸传感器

Flexible, Highly Sensitive Paper-Based Screen Printed MWCNT/PDMS Composite Breath Sensor for Human Respiration Monitoring.

作者信息

Thiyagarajan K, Rajini G K, Maji Debashis

机构信息

School of Electrical EngineeringVellore Institute of Technology Vellore 632 014 India.

Department of Sensor and Biomedical TechnologySchool of Electronics EngineeringVellore Institute of Technology Vellore 632 014 India.

出版信息

IEEE Sens J. 2020 Nov 27;21(13):13985-13995. doi: 10.1109/JSEN.2020.3040995. eCollection 2021 Jul 1.

Abstract

Accurate measurement and monitoring of respiration is vital in patients affected by severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2). Patients with severe chronic diseases and pneumonia need continuous respiration monitoring and oxygenation support. Existing respiratory sensing techniques require direct contact with the human body along with expensive and heavy Holter monitors for continuous real-time monitoring. In this work, we propose a low-cost, non-invasive and reliable paper-based wearable screen printed sensor for human respiration monitoring as an effective alternative of existing sensing systems. The proposed sensor was fabricated using traditional screen printing of multi-walled carbon nanotubes (MWCNTs) and polydimethylsiloxane (PDMS) composite based interdigitated electrodes on paper substrate. The paper substrate was used as humidity sensing material of the sensor. The hygroscopic nature of paper during inhalation and exhalation causes a change in dielectric constant, which in turn changes the capacitance of the sensor. The composite interdigitated electrode configuration exhibited better response times with a rise time of 1.178s being recorded during exhalation and fall time of 0.88s during inhalation periods. The respiration rate of sensor was successfully examined under various breathing conditions such as normal breathing, deep breathing, workout, oral breathing, nasal breathing, fast breathing and slow breathing by employing it in a wearable mask, a mandatory wearable product during the current COVID-19 pandemic situation.Thus, the above proposed sensor may hold tremendous potential in wearable/flexible healthcare technology with good sensitivity, stability, biodegradability and flexibility at this time of need.

摘要

对感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的患者进行准确的呼吸测量和监测至关重要。患有严重慢性疾病和肺炎的患者需要持续的呼吸监测和氧合支持。现有的呼吸传感技术需要与人体直接接触,同时还需要昂贵且笨重的动态心电图监测仪进行连续实时监测。在这项工作中,我们提出了一种低成本、非侵入性且可靠的纸质可穿戴丝网印刷传感器,用于人体呼吸监测,作为现有传感系统的有效替代方案。所提出的传感器是通过在纸质基板上对基于多壁碳纳米管(MWCNTs)和聚二甲基硅氧烷(PDMS)复合材料的叉指电极进行传统丝网印刷而制成的。纸质基板用作传感器的湿度传感材料。纸张在吸气和呼气过程中的吸湿性质会导致介电常数发生变化,进而改变传感器的电容。复合叉指电极配置表现出更好的响应时间,呼气时记录的上升时间为1.178秒,吸气时下降时间为0.88秒。通过将该传感器应用于可穿戴口罩(在当前新冠疫情期间的一种强制性可穿戴产品),成功地在各种呼吸条件下(如正常呼吸、深呼吸、锻炼、口呼吸、鼻呼吸、快速呼吸和缓慢呼吸)对传感器的呼吸速率进行了检测。因此,上述所提出的传感器在可穿戴/柔性医疗技术中可能具有巨大潜力,在当前需要时具有良好的灵敏度、稳定性、生物降解性和柔韧性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b91/8768993/6fd0fbfbc883/gk1abcdefghij-3040995.jpg

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