Department of Otolaryngology, 25044Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Department of Head and Neck Surgery, 12222David Geffen School of Medicine at University of California, Los Angeles, California.
Am J Rhinol Allergy. 2022 Nov;36(6):763-772. doi: 10.1177/19458924221110652. Epub 2022 Jul 5.
Tumors involving the anterior portion of the maxillary sinus remain technically challenging to access via an endoscopic approach. The modified endoscopic Denker's (MED) procedure was recently introduced to address such lesions. We present a multicenter series of 58 patients with tumors involving the anterior maxillary sinus successfully resected using a MED procedure and present the clinical outcomes and complications.
A multi-institution retrospective chart review was performed on patients who underwent the MED approach for the management of tumors involving the anterior maxillary sinus from 2009 to 2020. Demographic data, pathology, surgical outcomes, and complications were reviewed.
Fifty-eight patients were identified, including 34 (58.6%) male and 24 (41.4%) female patients. The most common pathologies included: inverted papilloma (n = 27; 46.6%), adenoid cystic carcinoma (n = 9; 15.5%), and squamous cell carcinoma (n = 8; 13.8%). Thirty-eight patients (65.5%) underwent MED alone, while 20 (34.5%) had combined expanded endonasal approaches for lesions extending beyond the maxillary sinus. All maxillary sinus lesions were successfully accessed with the MED procedure without the need for an additional approach. After a mean follow-up of 30 months (range, 1-127), 8 of 58 (13.8%) patients developed complications related to the MED, including epiphora requiring an additional procedure (n = 4; 6.9%), prolonged facial/palatal numbness (n = 3; 5.2%), severe epistaxis (n = 1; 1.7%), and vestibular stenosis (n = 1; 1.7%), the latter of which occurred following postoperative radiation.
The MED procedure is a safe and highly effective approach for benign and malignant tumors involving the anterior maxillary sinus. However, patients should be counseled preoperatively on potential complications including the risk of facial numbness and epiphora.
上颌窦前份肿瘤采用内镜入路仍具有一定技术挑战性。改良内镜 Denker 术(MED)最近被引入以处理此类病变。我们报告了 58 例采用 MED 手术成功切除累及前上颌窦肿瘤的多中心系列病例,并介绍了其临床结果和并发症。
对 2009 年至 2020 年间采用 MED 方法治疗累及前上颌窦肿瘤的患者进行多机构回顾性图表回顾。回顾了人口统计学数据、病理学、手术结果和并发症。
共确定了 58 例患者,其中男性 34 例(58.6%),女性 24 例(41.4%)。最常见的病理包括:内翻性乳头状瘤(n=27;46.6%)、腺样囊性癌(n=9;15.5%)和鳞状细胞癌(n=8;13.8%)。38 例(65.5%)患者单独接受 MED,20 例(34.5%)患者因病变超出上颌窦而联合行扩大的内镜鼻窦入路。所有上颌窦病变均成功通过 MED 手术获得,无需额外入路。在平均 30 个月(范围,1-127)的随访后,58 例患者中有 8 例(13.8%)发生与 MED 相关的并发症,包括需要进一步手术的溢泪(n=4;6.9%)、面部/ palate 麻木延长(n=3;5.2%)、严重鼻出血(n=1;1.7%)和前庭狭窄(n=1;1.7%),后者发生在术后放疗后。
MED 手术是治疗前上颌窦良性和恶性肿瘤的一种安全有效的方法。然而,应在术前告知患者潜在的并发症,包括面神经麻木和溢泪的风险。