Takahara Yutaka, Shionoya Ikuyo, Shioya Akihiro, Shinomiya Shohei, Oikawa Taku, Yamada Sohsuke, Mizuno Shiro
Department of Respiratory Medicine, Japan.
Department of Pathology and Laboratory Medicine, Kanazawa Medical University, 1-1 Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa, 920-0293, Japan.
Respir Med Case Rep. 2022 Jun 25;38:101694. doi: 10.1016/j.rmcr.2022.101694. eCollection 2022.
In cases wherein metastatic disease diagnosis in lung cancer is difficult with imaging, tissue biopsy should be performed. A 77-year-old woman presented with a complaint of cough. Positron emission tomography-computed tomography showed a left lung tumor with fluorodeoxyglucose accumulation, multiple lymphadenopathies, and right-rib sclerotic lesion. Although the diagnosis was lung adenocarcinoma, the bone lesion required differentiation from traumatic changes. A costal biopsy showed bone lesions as post-fracture healing changes, leading to variation in the therapeutic strategy to curative. In patients with lung cancer, history of trauma, and bone lesions with fluorodeoxyglucose accumulation, aggressive tissue biopsy is recommended for accurate staging.
在肺癌转移疾病的诊断通过影像学手段难以确定的情况下，应进行组织活检。一名77岁女性因咳嗽前来就诊。正电子发射断层扫描-计算机断层扫描显示左肺有一个伴有氟脱氧葡萄糖积聚的肿瘤、多处淋巴结肿大以及右肋骨硬化性病变。尽管诊断为肺腺癌，但骨病变需要与创伤性改变相鉴别。肋骨活检显示骨病变为骨折后愈合改变，这导致了治疗策略向根治性的转变。对于患有肺癌、有创伤史且伴有氟脱氧葡萄糖积聚的骨病变患者，建议进行积极的组织活检以准确分期。
