灭活脊髓灰质炎病毒疫苗在越南缩小了 2 型免疫差距。
Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam.
机构信息
Expanded Program on Immunizations Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Thanh Hoa Provincial CDC, Thanh Hoa, Vietnam.
出版信息
J Pediatric Infect Dis Soc. 2022 Sep 29;11(9):413-416. doi: 10.1093/jpids/piac046.
Abstract
This was a cross-sectional community-based serological survey of polio antibodies assessing the immunogenicity of inactivated poliovirus vaccine (IPV) focusing on poliovirus serotype 2. IPV was administered to 5-month-old children. Type 2 antibody seroprevalence when measured 1 month after IPV administration was >95%. One IPV dose successfully closed the immunity gap.
摘要
这是一项针对脊髓灰质炎病毒抗体的横断面社区血清学调查，评估了灭活脊髓灰质炎病毒疫苗（IPV）的免疫原性，重点关注脊髓灰质炎病毒血清型 2。IPV 接种于 5 月龄儿童。在 IPV 接种后 1 个月测量时，血清 2 型抗体阳性率>95%。一剂 IPV 成功地弥合了免疫差距。
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