Center for Clinical Evidence-Based and Translational Medicine, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China.
Department of Endocrinology, Daxing Hospital, Xi'an 710000, China.
Nutrients. 2022 Jun 27;14(13):2650. doi: 10.3390/nu14132650.
Although many studies have explored the relationship between total dietary fiber intake and the risk of chronic non-communicable diseases, the results are mixed. There is also a lack of research on the association between dietary fiber intake from different food sources and disease. Using data from the China Nutrition and Health Database from 2004 to 2015, Cox proportional risk models were used to explore the associations between total dietary fiber and fiber intake from different food sources and the occurrence of type 2 diabetes, hypertension, obesity, cardiovascular disease, and all-cause mortality. After multi-factorial adjustment, the hazard ratios (95% confidence interval) of total dietary fiber intake (quartile 4 vs. quartile 1) in type 2 diabetes, hypertension, obesity, cardiovascular disease, and all-cause mortality cohorts were 1.20 (0.93, 1.55), 0.91 (0.75, 1.12), 0.93 (0.64, 1.35), 1.13 (0.60, 2.12), 1.13 (0.60, 2.12), and 1.13 (0.84, 1.52). Whole-grain fiber intake was positively associated with hypertension but not with the occurrence of other diseases. No association was observed between legume fibers, fruit fibers, and vegetable fibers in the cohorts of type 2 diabetes, hypertension, obesity, cardiovascular diseases and all-cause mortality. Our study did not find any association between total dietary fiber and dietary fiber intake from different food sources and type 2 diabetes, obesity, cardiovascular disease, and all-cause mortality in the Chinese population. The role of dietary fiber in the Chinese population may be overestimated. More extraordinary efforts are needed to further confirm the association between dietary fiber and these diseases in the Chinese population.
虽然许多研究都探讨了总膳食纤维摄入量与慢性非传染性疾病风险之间的关系,但结果却存在差异。此外,对于不同食物来源的膳食纤维摄入量与疾病之间的关联也缺乏研究。本研究使用了 2004 年至 2015 年中国营养与健康数据库的数据,采用 Cox 比例风险模型探讨了总膳食纤维和不同食物来源的膳食纤维摄入量与 2 型糖尿病、高血压、肥胖、心血管疾病和全因死亡率发生的关系。经多因素调整后,2 型糖尿病、高血压、肥胖、心血管疾病和全因死亡率队列中膳食纤维总摄入量(四分位 4 与四分位 1)的风险比(95%置信区间)分别为 1.20(0.93,1.55)、0.91(0.75,1.12)、0.93(0.64,1.35)、1.13(0.60,2.12)、1.13(0.60,2.12)和 1.13(0.84,1.52)。全谷物纤维摄入量与高血压呈正相关,但与其他疾病的发生无关。在 2 型糖尿病、高血压、肥胖、心血管疾病和全因死亡率队列中,豆类纤维、水果纤维和蔬菜纤维与这些疾病的发生均无关联。本研究在中国人群中未发现总膳食纤维和不同食物来源的膳食纤维摄入量与 2 型糖尿病、肥胖、心血管疾病和全因死亡率之间存在任何关联。膳食纤维在中国人群中的作用可能被高估了。需要付出更多努力来进一步证实膳食纤维与这些疾病在中国人群中的关联。