Division of Hepatobiliary. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Acta Med Indones. 2022 Apr;54(2):324-346.
Portal hypertension is a clinical syndrome that consists of hypersplenism, ascites, gastroesophageal varices, and encephalopathy. This condition is marked by increased portal pressure gradient and may occur with or without liver cirrhosis. To date, portal hypertension remains as the leading cause of severe complications and death of a patient with chronic liver disease, especially liver cirrhosis. Therefore, thorough understanding about management of portal hypertension is strongly required, especially considering that many complications of portal hypertension require early diagnosis and treatment to improve the prognosis of the patients. Additionally, although hepatic venous pressure gradient (HVPG) measurement has become a gold standard procedure for measuring portal pressure in the last twenty years, utilization of this method in Indonesia has been hindered by reluctance of the patients due to its invasiveness, high cost, and limited availability. This consensus is developed with evidence-based medicine principles to provide a guideline for portal hypertension management for general practitioners, specialists, and consultants, to achieve better clinical outcomes of portal hypertension in Indonesia. Keywords: portal hypertension, liver cirrhosis, chronic liver disease.
门静脉高压症是一种临床综合征,包括脾功能亢进、腹水、胃食管静脉曲张和脑病。这种情况的特点是门静脉压力梯度增加,可能伴有或不伴有肝硬化。迄今为止,门静脉高压症仍然是慢性肝病患者(尤其是肝硬化患者)严重并发症和死亡的主要原因。因此,强烈需要彻底了解门静脉高压症的管理,特别是考虑到门静脉高压症的许多并发症需要早期诊断和治疗,以改善患者的预后。此外,尽管肝静脉压力梯度(HVPG)测量在过去二十年中已成为测量门静脉压力的金标准程序,但由于其侵袭性、高成本和有限的可用性,该方法在印度尼西亚的应用受到了患者的抵制。本共识是基于循证医学原则制定的,旨在为普通医生、专家和顾问提供门静脉高压症管理指南,以实现印度尼西亚门静脉高压症更好的临床结果。关键词:门静脉高压症,肝硬化,慢性肝病。