Bennett Sadie, Tafuro Jacopo, Brumpton Marcus, Bardolia Caragh, Heatlie Grant, Duckett Simon, Ridley Paul, Nanjaiah Prakash, Kwok Chun Shing
Heart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Keele University, Stoke-on-Trent, UK.
Echo Res Pract. 2022 Jul 13;9(1):4. doi: 10.1186/s44156-022-00004-7.
Mitral annular disjunction (MAD) is a structural abnormality characterized by the distinct separation of the mitral valve annulus/left atrium wall and myocardium. Little is known about the significance of MAD in patients requiring mitral valve surgery. This evaluation evaluates the echocardiographic characteristics and patient outcomes for patients with and without MAD who require mitral valve surgery.
All patients who underwent mitral valve surgery and who had a pre-surgical transthoracic echocardiogram between 2013 and 2020 were included. Patient demographics and clinical outcomes were collected on review of patient electronic records.
A total of 185 patients were included in the analysis of which 32.4% had MAD (average MAD length 8.4 mm). MAD was seen most commonly in patients with mitral valve prolapse and myxomatous mitral valves disease (90% and 60% respectively). In the patients with MAD prior to mitral valve surgery, only 3.9% had MAD post mitral valve surgery. There were no significant difference in the severity of post-operative mitral regurgitation, arrhythmic events or major adverse cardiovascular events in patients with and without MAD.
MAD is common in patients who undergo mitral valve surgery. Current surgical techniques are able to correct the MAD abnormality in the vast majority of patients. MAD is not associated with an increased risk of adverse clinical outcomes post mitral valve surgery.
二尖瓣环分离(MAD)是一种结构异常,其特征为二尖瓣环/左心房壁与心肌明显分离。对于需要进行二尖瓣手术的患者,MAD的意义鲜为人知。本评估旨在评价需要二尖瓣手术的有或无MAD患者的超声心动图特征及患者预后。
纳入2013年至2020年间接受二尖瓣手术且术前有经胸超声心动图检查的所有患者。通过查阅患者电子记录收集患者人口统计学资料和临床结局。
共有185例患者纳入分析,其中32.4%有MAD(平均MAD长度8.4毫米)。MAD最常见于二尖瓣脱垂和黏液瘤样二尖瓣疾病患者(分别为90%和60%)。在二尖瓣手术前有MAD的患者中,二尖瓣手术后仅有3.9%仍有MAD。有或无MAD的患者在术后二尖瓣反流严重程度、心律失常事件或主要不良心血管事件方面无显著差异。
MAD在接受二尖瓣手术的患者中很常见。目前的手术技术能够在绝大多数患者中纠正MAD异常。MAD与二尖瓣手术后不良临床结局风险增加无关。