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对乳头进行长时间电刺激可引起麻醉状态下泌乳大鼠间歇性排乳。

Prolonged electrical stimulation of the nipples evokes intermittent milk ejection in the anaesthetised lactating rat.

作者信息

Sutherland R C, Juss T S, Wakerley J B

出版信息

Exp Brain Res. 1987;66(1):29-34. doi: 10.1007/BF00236198.

DOI:10.1007/BF00236198
PMID:3582533
Abstract

Intermittent and continuous electrical stimulation of the nipples elicited milk-ejection responses in the lactating rat. The responses occurred intermittently, with similar amplitudes and periodicity as those seen in suckled rats. The responses were always associated with synchronization of the electroencephalogram (EEG), but some rats with synchronized EEG activity did not milk eject during stimulation. Since continuous stimulation also resulted in intermittent milk ejection it seems unlikely that the periodicity of the reflex in suckled rats depends upon changes in the intensity of sensory stimulation. The techniques of nipple stimulation may be a useful method with which to study neural pathways and other phenomena such as gating involved in oxytocin release and milk ejection. The success of the technique depends on a variety of factors such as parameters of the stimulation and state of anaesthesia.

摘要

对哺乳期大鼠的乳头进行间歇性和持续性电刺激可引发排乳反应。这些反应呈间歇性发生,其幅度和周期性与哺乳大鼠所见相似。这些反应总是与脑电图(EEG)的同步化相关,但有些脑电图活动同步化的大鼠在刺激过程中并未排乳。由于持续刺激也会导致间歇性排乳,因此哺乳大鼠反射的周期性似乎不太可能取决于感觉刺激强度的变化。乳头刺激技术可能是一种有用的方法,可用于研究神经通路以及其他现象,如催产素释放和排乳过程中涉及的门控现象。该技术的成功取决于多种因素,如刺激参数和麻醉状态。

相似文献

1
Prolonged electrical stimulation of the nipples evokes intermittent milk ejection in the anaesthetised lactating rat.对乳头进行长时间电刺激可引起麻醉状态下泌乳大鼠间歇性排乳。
Exp Brain Res. 1987;66(1):29-34. doi: 10.1007/BF00236198.
2
[The dynamics of the milk ejection reflex in lactating rats with mechanical stimulation of their nipples].[机械刺激乳头的泌乳大鼠排乳反射的动力学]
Fiziol Zh SSSR Im I M Sechenova. 1991 Jan;77(1):128-32.
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Sleep: a prerequisite for reflex milk ejection in the rat.睡眠:大鼠反射性排乳的一个前提条件。
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引用本文的文献

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Unsolved Mysteries of the Human Mammary Gland: Defining and Redefining the Critical Questions from the Lactation Consultant's Perspective.人类乳腺的未解之谜:从泌乳顾问的角度定义和重新定义关键问题
J Mammary Gland Biol Neoplasia. 2014 Dec;19(3-4):271-88. doi: 10.1007/s10911-015-9330-7. Epub 2015 Jun 18.
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A bold view of the lactating brain: functional magnetic resonance imaging studies of suckling in awake dams.哺乳期大脑的大胆观点:清醒母鼠哺乳时的功能磁共振成像研究。
J Neuroendocrinol. 2011 Nov;23(11):1009-19. doi: 10.1111/j.1365-2826.2011.02184.x.
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Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland.

本文引用的文献

1
Neurohormonal mechanisms in emotional inhibition of milk ejection.情绪性抑制乳汁排出的神经激素机制。
J Endocrinol. 1955 Jan;12(1):29-37. doi: 10.1677/joe.0.0120029.
2
Effect of the suckling stimulus on secretion of prolactin and luteinizing hormone in conscious and anaesthetized rats.
J Endocrinol. 1980 Dec;87(3):437-44. doi: 10.1677/joe.0.0870437.
3
Sleep: a prerequisite for reflex milk ejection in the rat.睡眠:大鼠反射性排乳的一个前提条件。
Exp Brain Res. 1980 Jan;38(2):151-62. doi: 10.1007/BF00236736.
大鼠乳腺乳头中的降钙素基因相关肽(CGRP)。
Histochemistry. 1994 Dec;102(6):437-44. doi: 10.1007/BF00269575.
4
Mesencephalic areas controlling pulsatile oxytocin release in the suckled rat.控制哺乳大鼠中脉冲式催产素释放的中脑区域。
J Endocrinol. 1981 Nov;91(2):233-44. doi: 10.1677/joe.0.0910233.
5
Reproducible increases in intramammary pressure after spinal cord stimulation in lactating rats.
Exp Brain Res. 1984;55(2):313-6. doi: 10.1007/BF00237281.
6
Effect of auditory, olfactory and optic stimuli upon milk ejection and suckling-induced release of prolactin in lactating rats.听觉、嗅觉和视觉刺激对泌乳大鼠乳汁排出及吮乳诱导的催乳素释放的影响。
Endocrinology. 1967 May;80(5):840-6. doi: 10.1210/endo-80-5-840.
7
The milk-ejection reflex of the rat: an intermittent function not abolished by surgical levels of anaesthesia.大鼠的排乳反射:一种间歇性功能,不会因手术麻醉水平而消失。
J Endocrinol. 1973 Jun;57(3):459-76. doi: 10.1677/joe.0.0570459.
8
Evidence for a spinal site at which opioids may act to inhibit the milk-ejection reflex.有证据表明存在一个脊髓部位,阿片类药物可能在此处发挥作用以抑制射乳反射。
J Endocrinol. 1985 Sep;106(3):401-7. doi: 10.1677/joe.0.1060401.
9
Plasma concentrations of prolactin and thyrotrophin during suckling in urethane-anaesthetized rats.
J Endocrinol. 1976 Sep;70(3):429-37. doi: 10.1677/joe.0.0700429.
10
Endocrine neurons.
Recent Prog Horm Res. 1975;31:243-94. doi: 10.1016/b978-0-12-571131-9.50011-6.