Faxén A, Alpsten M, Cederblad A, Kewenter J, Rossander L
Scand J Gastroenterol. 1978;13(6):727-33. doi: 10.3109/00365527809181788.
A new technique is described whereby gastric emptying of a 51Cr-labelled solid meal (hamburger, vegetables, potatoes) was measured by way of a movable NaJ(T1) detector. The technique allowed separate measurements over the proximal and the distal part of the stomach. Seven volunteers took part in a study which revealed good correlation between two individual consecutive tests. Eight patients who took part in a controlled randomized series of parietal cell vagotomy (PCV) versus total gastric selective vagotomy and pyloroplasty (SV+P) underwent the test preoperatively and 6 to 8 months postoperatively. Following both operations gastric emptying was retarded. The time taken for the amount of meal remaining in the stomach to be reduced to 75,50 and 25% respectively was significantly longer postoperatively than before surgery, but there were no differences in this respect between PCV and SV+P. The retardation of gastric emptying of solids was in contrast to the emptying of 10% glucose solution, which in the same series of patients was found to be accelerated. Following PCV there was a change in the distribution of the meal within the stomach immediately after the intake of the meal: a larger part of the meal was found in the proximal stomach post-operatively than before operation. There was no significant change in this intragastric distribution of the meal after SV+P.
本文描述了一种新技术，通过可移动的碘化钠（铊）探测器测量51铬标记固体餐（汉堡、蔬菜、土豆）的胃排空情况。该技术能够分别测量胃近端和远端的排空情况。七名志愿者参与了一项研究，结果显示两次连续个体测试之间具有良好的相关性。八名参与壁细胞迷走神经切断术（PCV）与全胃选择性迷走神经切断术加幽门成形术（SV+P）对照随机系列研究的患者，在术前和术后6至8个月接受了该测试。两种手术后胃排空均延迟。胃内剩余食物量分别减少至75%、50%和25%所需的时间，术后明显长于术前，但PCV和SV+P在这方面没有差异。固体食物胃排空延迟与10%葡萄糖溶液的排空情况形成对比，在同一组患者中发现葡萄糖溶液排空加速。PCV术后进食后立即出现胃内食物分布的变化：术后近端胃内的食物量比术前更多。SV+P术后胃内食物的这种分布没有显著变化。
