Division of Emergency Medicine, University of Cape Town, Cape Town, South Africa.
Department of Anaesthesia and Perioperative Medicine, University of Cape Town, Cape Town, South Africa.
BMC Emerg Med. 2022 Jul 16;22(1):129. doi: 10.1186/s12873-022-00688-4.
Prehospital advanced airway management, including endotracheal intubation (ETI), is one of the most commonly performed advanced life support skills. In South Africa, prehospital ETI is performed by non-physician prehospital providers. This practice has recently come under scrutiny due to lower first pass (FPS) and overall success rates, a high incidence of adverse events (AEs), and limited evidence regarding the impact of ETI on mortality. The aim of this study was to describe non-physician ETI in a South African national sample in terms of patient demographics, indications for intubation, means of intubation and success rates. A secondary aim was to determine what factors were predictive of first pass success.
This study was a retrospective chart review of prehospital ETIs performed by non-physician prehospital providers, between 01 January 2017 and 31 December 2017. Two national private Emergency Medical Services (EMS) and one provincial public EMS were sampled. Data were analysed descriptively and summarised. Logistic regression was performed to evaluate factors that affect the likelihood of FPS.
A total of 926 cases were included. The majority of cases were adults (n = 781, 84.3%) and male (n = 553, 57.6%). The most common pathologies requiring emergency treatment were head injury, including traumatic brain injury (n = 328, 35.4%), followed by cardiac arrest (n = 204, 22.0%). The mean time on scene was 46 minutes (SD = 28.3). The most cited indication for intubation was decreased level of consciousness (n = 515, 55.6%), followed by cardiac arrest (n = 242, 26.9%) and ineffective ventilation (n = 96, 10.4%). Rapid sequence intubation (RSI, n = 344, 37.2%) was the most common approach. The FPS rate was 75.3%, with an overall success rate of 95.7%. Intubation failed in 33 (3.6%) patients. The need for ventilation was inversely associated with FPS (OR = 0.42, 95% CI: 0.20-0.88, p = 0.02); while deep sedation (OR = 0.56, 95% CI: 0.36-0.88, p = 0.13) and no drugs (OR = 0.47, 95% CI: 0.25-0.90, p = 0.02) compared to RSI was less likely to result in FPS. Increased scene time (OR = 0.99, 95% CI: 0.985-0.997, p < 0.01) was inversely associated FPS.
This is one of the first and largest studies evaluating prehospital ETI in Africa. In this sample of ground-based EMS non-physician ETI, we found success rates similar to those reported in the literature. More research is needed to determine AE rates and the impact of ETI on patient outcome. There is an urgent need to standardise prehospital ETI reporting in South Africa to facilitate future research.
院前高级气道管理,包括气管内插管(ETI),是最常进行的高级生命支持技能之一。在南非,非医师院前提供者进行院前 ETI。由于首次通过(FPS)和总体成功率较低、不良事件(AE)发生率较高以及 ETI 对死亡率影响的证据有限,这种做法最近受到了审查。本研究的目的是描述南非国家样本中非医师 ETI 在患者人口统计学、插管指征、插管方式和成功率方面的情况。次要目的是确定哪些因素是首次通过成功的预测因素。
这是一项对非医师院前提供者在 2017 年 1 月 1 日至 12 月 31 日期间进行的院前 ETI 的回顾性图表审查。抽取了两个国家私人紧急医疗服务(EMS)和一个省级公共 EMS。数据以描述性方式进行分析和总结。进行逻辑回归以评估影响 FPS 可能性的因素。
共纳入 926 例病例。大多数病例为成年人(n=781,84.3%)和男性(n=553,57.6%)。需要紧急治疗的最常见病症是头部损伤,包括创伤性脑损伤(n=328,35.4%),其次是心脏骤停(n=204,22.0%)。现场平均时间为 46 分钟(SD=28.3)。最常引用的插管指征是意识水平降低(n=515,55.6%),其次是心脏骤停(n=242,26.9%)和无效通气(n=96,10.4%)。快速序列插管(RSI,n=344,37.2%)是最常见的方法。FPS 率为 75.3%,总体成功率为 95.7%。33 例(3.6%)患者插管失败。需要通气与 FPS 呈负相关(OR=0.42,95%CI:0.20-0.88,p=0.02);而深度镇静(OR=0.56,95%CI:0.36-0.88,p=0.13)和无药物(OR=0.47,95%CI:0.25-0.90,p=0.02)与 RSI 相比,FPS 更不可能成功。现场时间增加(OR=0.99,95%CI:0.985-0.997,p<0.01)与 FPS 呈负相关。
这是评估非洲院前 ETI 的首批和最大规模的研究之一。在本地面基 EMS 非医师 ETI 的样本中,我们发现成功率与文献报道相似。需要进一步研究以确定 AE 发生率以及 ETI 对患者结局的影响。迫切需要在南非规范院前 ETI 报告,以促进未来的研究。