Stemkens Ralf, Schouten Jeroen A, van Kessel Sophie A M, Akkermans Reinier P, Telgt Denise S C, Fleuren Hanneke W H A, Claassen Mark A A, Hulscher Marlies E J L, Ten Oever Jaap
Department of Pharmacy and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Intensive Care Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Clin Microbiol Infect. 2023 Feb;29(2):182-187. doi: 10.1016/j.cmi.2022.07.007. Epub 2022 Jul 15.
Antimicrobial stewardship (AMS) teams are responsible for performing an AMS programme in their hospitals that aims to improve the quality of antibiotic use. Measuring the quality of antimicrobial use is a core task of a stewardship team. Measurement provides insight into the current quality of antibiotic use and allows for the establishment of goals for improvement. Yet, a practical description of how such a quality measurement using quality indicators (QIs) should be performed is lacking.
To provide practical guidance on how a stewardship team can use QIs to measure the quality of antibiotic use in their hospital and identify targets for improvement.
General principles from implementation science, peer-reviewed publications, and experience from clinicians and researchers with AMS experience.
We provide step-by-step guidance on how AMS teams can use QIs to measure the quality of antibiotic use. The principles behind each step are explained and illustrated with the description and results of an audit of patients receiving outpatient parenteral antimicrobial therapy in four Dutch hospitals.
Improving the quality of antibiotic use is impossible without first gaining insight into that quality by performing a measurement with validated QIs. This step-by-step practice example of how to use quality indicators in a hospital will help AMS teams to identify targets for improvement. This enables them to perform their AMS programme more effectively and efficiently.
抗菌药物管理（AMS）团队负责在其医院开展抗菌药物管理计划，旨在提高抗生素使用质量。衡量抗菌药物使用质量是管理团队的核心任务。测量可深入了解当前抗生素使用质量，并有助于设定改进目标。然而，目前缺乏关于如何使用质量指标（QIs）进行此类质量测量的实际描述。
为管理团队如何使用质量指标来衡量其医院抗生素使用质量并确定改进目标提供实用指南。
实施科学的一般原则、同行评审出版物以及有抗菌药物管理经验的临床医生和研究人员的经验。
我们提供了关于AMS团队如何使用质量指标来衡量抗生素使用质量的分步指南。对荷兰四家医院接受门诊胃肠外抗菌治疗的患者进行的一项审计的描述和结果，解释并说明了每一步背后的原则。
如果不首先通过使用经过验证的质量指标进行测量来深入了解抗生素使用质量，就不可能提高其质量。这个关于如何在医院使用质量指标的分步实践示例将帮助AMS团队确定改进目标。这使他们能够更有效、更高效地开展其抗菌药物管理计划。
