Hadzine Youssef, Elmekkaoui Adel, Benlenda Othmane, Wakrim Soukaina, Nassik Hicham
Department of Anesthesiology and Reanimation, Faculty of Medicine and Pharmacy of Agadir, University Ibn Zohr, Agadir, Morocco.
Department of Radiology, Faculty of Medicine and Pharmacy of Agadir, University ibn zohr, Agadir, Morocco.
Radiol Case Rep. 2022 Jul 9;17(9):3291-3293. doi: 10.1016/j.radcr.2022.06.018. eCollection 2022 Sep.
Periventricular focal nodular heterotopia is a rare secondary cerebral distortion caused by the interruption of neuronal migration from the periventricular germinal zone to the cortex during the fetal period. Clinically, it may manifest as epilepsy resistant to pharmacological treatments or rarely as mental retardation. We report a case of a six years-old male child who was subject to the intensive care unit for the management of refractory epilepsy. The diagnosis was done by magnetic resonance imaging of the brain, which revealed a nodular periventricular heterotopia of the gray matter. After the management of the status of epilepticus, the child remained spastic, aphasic with no contact with his environment.
脑室周围局灶性结节性异位是一种罕见的继发性脑畸形，由胎儿期神经元从脑室周围生发区向皮质迁移中断所致。临床上，它可能表现为对药物治疗耐药的癫痫，或很少表现为智力迟钝。我们报告一例6岁男童，因难治性癫痫入住重症监护病房。通过脑部磁共振成像做出诊断，显示脑室周围灰质结节性异位。在癫痫持续状态得到处理后，该患儿仍有痉挛、失语，与外界无交流。
