Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, California, U.S.A.
Division of General Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Salivary Gland Center, University of California San Francisco, San Francisco, California, U.S.A.
Laryngoscope. 2023 Apr;133(4):792-800. doi: 10.1002/lary.30294. Epub 2022 Jul 18.
The objective is to evaluate the long-term impact of sialendoscopic-assisted salivary duct surgery (SASDS) on sialadenitis symptoms using the Chronic Obstructive Sialadenitis Symptoms (COSS) questionnaire.
The COSS questionnaire, which scores symptoms on a 0-100 scale, was administered prospectively to adult patients pre-operatively, 1-year, and 6-years post-operatively. We examined COSS scores and categories representing complete (<10), partial (10-25), and no (>25) resolution of symptoms with attention to factors significantly associated with incomplete resolution (≥10).
Approximately 6-years after SASDS, 111 patients reported scores for 128 symptomatic glands (72 with sialolithiasis, 56 without sialolithiasis). For glands with sialolithiasis, the median COSS score pre-SASDS was 27.5 (interquartile range [IQR]: 13.5-43), which was significantly reduced to 1.0 (IQR: 0-5.5) at 1-year and 1.5 (IQR 0-5) at 6-years postoperatively. Glands without sialolithiasis had a median COSS score of 40.5 (IQR: 23-52.5) preoperatively, that significantly reduced to 13.5 (IQR 5-21) at 1-year and 14 (IQR 6.5-25.5) at 6-years post-operatively. There was no significant difference in scores from 1- to 6-years. Intraoperative presence of sialolith, absence of stenosis, stenosis in the distal duct, and submandibular gland involvement were significant predictors of complete resolution of symptoms at 6-years.
Approximately 6-years after SASDS for sialadenitis, the majority of patients have durable symptom improvement. The sialolithiasis group had higher rates of complete resolution compared to the non-sialolithiasis group. Presence of ductal stenosis on sialendoscopy, non-distal stenoses, and parotid gland involvement were risk factors for persistent long-term sialadenitis symptoms. Laryngoscope, 133:792-800, 2023.
本研究旨在使用慢性阻塞性唾液腺炎症状(COSS)问卷评估涎腺内窥镜辅助唾液腺手术(SASDS)对唾液腺炎症状的长期影响。
前瞻性地向成年患者术前、术后 1 年和 6 年使用 COSS 问卷(0-100 分评分)进行评分,以评估症状完全缓解(<10 分)、部分缓解(10-25 分)和无缓解(>25 分)的患者。我们关注与不完全缓解(≥10 分)显著相关的因素,并检查 COSS 评分和代表症状完全缓解的类别。
SASDS 后约 6 年,111 例患者报告了 128 个有症状腺体(72 个有涎石,56 个无涎石)的评分。对于有涎石的腺体,术前 COSS 评分中位数为 27.5(四分位距[IQR]:13.5-43),术后 1 年和 6 年分别显著降低至 1.0(IQR:0-5.5)和 1.5(IQR:0-5)。术前无涎石的腺体 COSS 评分中位数为 40.5(IQR:23-52.5),术后 1 年和 6 年分别显著降低至 13.5(IQR:5-21)和 14(IQR:6.5-25.5)。1 年至 6 年的评分无显著差异。术中存在涎石、无狭窄、远端导管狭窄和颌下腺受累是 6 年时症状完全缓解的显著预测因素。
SASDS 治疗唾液腺炎后约 6 年,大多数患者的症状持续改善。涎石症组的完全缓解率高于非涎石症组。涎腺内窥镜下存在导管狭窄、非远端狭窄和腮腺受累是持续性长期唾液腺炎症状的危险因素。《喉镜》,133:792-800,2023 年。