Extracutaneous sporotrichosis.

Although an uncommon cause of arthritis, sporotrichosis may mimic other forms of joint disease and should be considered in the differential diagnosis of a patient with a chronic monoarticular arthritis or if granulomatous synovitis is recognized by histologic examination. Characteristic skin findings may be absent, repeated cultures may be necessary, severe osseous destructive changes can occur, and surgical extirpation of the diseased tissue combined with amphotericin B chemotherapy is recommended.