Guzzo Enzo Maris, Agranatti Alejo, Smith José, Larre Nicolás, Rozic Pablo, Krupitzki Hugo, Vieta Eduard, Vazquez Gustavo, Vinacour Carlos
Departamento de Psiquiatría, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Ciudad Autónoma de Buenos Aires, Argentina.
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Vertex. 2022 Jun;33(156):16-24. doi: 10.53680/vertex.v33i156.175.
Bipolar Disorders (BD) are a mood disorders group charactered by recurrent manic or hypomanic episodes, alternating with depressive episodes. Its prevalence is 4%, and several studies have shown that they generate disability. There are effective therapeutic options for acute episodes. However, the ultimate goal is to achieve functional recovery and adequate well-being.
There was done in Buenos Aires, Argentina a cross-sectional study comparing psychosocial functioning, with the Functioning Assessment Short Test (FAST) and subjective well-being with the Five Well-Being Index (WHO-5), among a sample of stabilized BD patients undergoing treatment at the Center of Medical Education and Clinical Research (Centro de Educación Médica e Investigaciones Clínicas) and the Bipolar Foundation (Fundación Bipolares de Argentina), with a control group.
A total of 102 BD patients and 52 controls where included. The FAST mean for patients and controls was 20.71 and 9.73 respectively (P=0.0000). The WHO-5 mean for patients was 59.11 and 69.76 for controls (P=0.0011). More than 70% of the patients presented functional alteration (FAST ≥12), and almost 35% presented inadequate subjective well-being (WHO-5 ≤52). Depressive symptoms conditioned worse scores on both scales. FAST scores were better among those who participated in mutual aid groups (P=0.026). While patients who underwent psychoeducation and those who received anticonvulsant drugs, presented better WHO-5 scores (P = 0.028 and P=0.048 respectively).
Patients with BD showed poor Functionality and poor Well-being despite being stabilized. There is direct relationship between both conditions. Depressive symptoms generated worst scores on the scales.
双相情感障碍(BD)是一组以反复出现躁狂或轻躁狂发作为特征的心境障碍,与抑郁发作交替出现。其患病率为4%,多项研究表明它们会导致残疾。急性发作有有效的治疗选择。然而,最终目标是实现功能恢复和充分的幸福感。
在阿根廷布宜诺斯艾利斯进行了一项横断面研究,比较了在医学教育与临床研究中心(Centro de Educación Médica e Investigaciones Clínicas)和阿根廷双相情感障碍基金会(Fundación Bipolares de Argentina)接受治疗的稳定期BD患者样本与对照组在心理社会功能方面的差异,使用功能评估简短测试(FAST)和主观幸福感方面的差异,使用五福指数(WHO-5)。
共纳入102例BD患者和52例对照组。患者和对照组的FAST平均值分别为20.71和9.73(P=0.0000)。患者的WHO-5平均值为59.11,对照组为69.76(P=0.0011)。超过70%的患者存在功能改变(FAST≥12),近35%的患者主观幸福感不足(WHO-5≤52)。抑郁症状在两个量表上的得分都更差。参加互助小组的患者FAST得分更好(P=0.026)。接受心理教育的患者和接受抗惊厥药物治疗的患者,WHO-5得分更高(分别为P = 0.028和P=0.048)。
BD患者尽管病情稳定,但功能和幸福感较差。这两种情况之间存在直接关系。抑郁症状在量表上的得分更差。