Karashima Eiji, Soga Yoshimitsu, Arima Takeshi, Noda Hirotaka, Yasuda Shioto, Kaneko Takeo
Department of Cardiology, Shimonoseki City Hospital, 1-13-1 Kouyou-chou, Shimonoseki, Yamaguchi, 750-8520, Japan.
Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
CVIR Endovasc. 2022 Jul 21;5(1):34. doi: 10.1186/s42155-022-00313-2.
To evaluate the efficacy of the GLadIus MG drilLINg technique (GLIMGLIN), a novel initial wiring technique using the Gladius MG™ structural features, for crossing the superficial femoral artery (SFA) with chronic total occlusion (CTO).
This retrospective, single-center study enrolled 27 symptomatic patients (mean age 77.4 ± 8.5 years; 20 men) with de novo SFA CTO (mean CTO length 16.1 ± 8.9 cm) who underwent GLIMGLIN as the initial wiring between January 2020 and December 2021. The success of GLIMGLIN was defined when the wire crossing was completed using a Gladius MG™ and a microcatheter without any additional devices and techniques.
The success rate of GLIMGLIN was 48.1%. Intravascular ultrasound findings showed complete true lumen passage in the GLIMGLIN success group. Compared to the failure group, the proximal (6.3 ± 0.8 vs. 5.5 ± 0.9 mm, p = 0.02) and distal (5.9 ± 0.5 vs. 5.4 ± 0.6 mm, p = 0.02) reference vessel diameters were significantly larger, and the rate of calcium angle > 180° was significantly lower (30.8 vs. 71.4%, p = 0.04) in the success group. No significant difference was shown in the CTO length between two groups. Total wiring time, total procedure time, and fluoroscopic time were significantly shorter in the success group.
GLIMGLIN may enable operators to perform CTO wiring easily and efficiently in selected cases.
为评估GladIus MG钻孔技术（GLIMGLIN）——一种利用Gladius MG™结构特征的新型初始导丝技术——用于穿过慢性完全闭塞（CTO）的股浅动脉（SFA）的疗效。
这项回顾性单中心研究纳入了27例有症状的患者（平均年龄77.4±8.5岁；20例男性），这些患者为初发SFA CTO（平均CTO长度16.1±8.9厘米），于2020年1月至2021年12月期间接受GLIMGLIN作为初始导丝操作。当使用Gladius MG™和微导管在不使用任何额外设备和技术的情况下完成导丝穿过时，定义为GLIMGLIN成功。
GLIMGLIN的成功率为48.1%。血管内超声检查结果显示，GLIMGLIN成功组实现了完全的真腔通过。与失败组相比，成功组的近端（6.3±0.8 vs. 5.5±0.9毫米，p = 0.02）和远端（5.9±0.5 vs. 5.4±0.6毫米，p = 0.02）参考血管直径显著更大，且成功组中钙角>180°的比例显著更低（30.8% vs. 71.4%，p = 0.04）。两组之间的CTO长度无显著差异。成功组的总导丝操作时间、总手术时间和透视时间显著更短。
GLIMGLIN可能使操作者在选定病例中轻松、高效地进行CTO导丝操作。
