Graduate School of Health Sciences, Doctoral Course, Kagoshima University Graduate School, 8-35, Sakuragaoka, Kagoshima-city, Kagoshima, 890-8544, Japan; The Yamabiko Medical Welfare Center, Rehabilitation Department, 1779, Minayoshi, Kagoshima-city, Kagoshima, 891-1206, Japan.
The Yamabiko Medical Welfare Center, Rehabilitation Department, 1779, Minayoshi, Kagoshima-city, Kagoshima, 891-1206, Japan.
Clin Nutr ESPEN. 2022 Aug;50:191-195. doi: 10.1016/j.clnesp.2022.05.018. Epub 2022 May 30.
We aimed to evaluate the usefulness of the bioelectrical impedance analysis method in the nutritional assessment of patients with severe motor and intellectual disabilities.
Eighty patients with severe motor and intellectual disabilities were included in the study, and the samples collected were biochemical and body composition data were obtained from regular blood samples and using the bioelectrical impedance analysis method. Nutritional status was scored from the biochemical data, and the subjects were divided into three groups: well-nourished, mildly malnourished, and moderately malnourished.
The data that changed significantly with worsening nutritional status were serum albumin, total lymphocyte count, skeletal muscle ratio, phase angle, edema index, and body cell mass normalized by height. There were no significant differences in total lymphocyte count and body cell mass normalized by height between the groups.
phase angle and edema index, which have been reported to be useful in nutritional assessment, responded sensitively to this nutritional score. Skeletal muscle ratio, which has been reported less frequently, has also been suggested to be useful in the nutritional assessment of severe motor and intellectual disabilities.
Low skeletal muscle ratio, low phase angle, and high edema index were significantly suggestive of malnutrition in patients with severe motor and intellectual disabilities, and correlated significantly with biochemical data, a conventional nutritional index. Therefore, bioelectrical impedance analysis is a useful method for nutritional assessment in patients with severe motor and intellectual disabilities.
评估生物电阻抗分析方法在严重运动和智力障碍患者营养评估中的作用。
纳入 80 例严重运动和智力障碍患者,采集生化和人体成分数据,使用生物电阻抗分析方法。根据生化数据进行营养状况评分,将患者分为营养良好、轻度营养不良和中度营养不良三组。
随着营养状况恶化而显著变化的数据为血清白蛋白、总淋巴细胞计数、骨骼肌比率、相位角、水肿指数和身高标准化的细胞内液量。三组间总淋巴细胞计数和身高标准化的细胞内液量无显著差异。
已有研究表明相位角和水肿指数对营养评估敏感,本研究中这两个指标对该营养评分的反应也很灵敏。骨骼肌比率的报道较少,但也提示其对严重运动和智力障碍患者的营养评估有用。
低骨骼肌比率、低相位角和高水肿指数强烈提示严重运动和智力障碍患者存在营养不良,与生化数据等传统营养指标显著相关。因此,生物电阻抗分析是严重运动和智力障碍患者营养评估的一种有用方法。