Paul T, Luhmer I, Stolke D, Becker H, Kallfelz H C
Monatsschr Kinderheilkd. 1987 Mar;135(3):166-9.
A Blalock-Taussig-anastomosis was performed at the age of 2 years in a boy with transposition of the great arteries, ventricular septal defect, and pulmonary atresia. Nine years later he developed a transient aphasia. Cranial computed tomography (CT-scan) revealed a structure compatible with brain abscess. The boy was conscious and no neurological deficit was found. Initial therapy consisted of Ampicillin, Tobramycin, and Metronidazole, 12 days later an acute hemiplegia developed. 30 ml of pus were aspirated from the brain abscess, and the boy's condition dramatically improved. Streptococcus milleri was found bacteriologically and antibiotic therapy was continued over six weeks. Serial CT-scans during and after therapy demonstrated disappearance of the brain abscess. The presented case shows that after a shunt procedure in cyanotic heart disease right-to-left-shunting and therefore chronic oxygen desaturation and polycythemia are still present as facilitating factors for focal encephalomalacia, cerebritis, and brain abscess. In case of short duration of neurological symptoms and a size of abscess less than 4 cm in diameter antibiotic therapy without total excision may eliminate the infection.
一名患有大动脉转位、室间隔缺损和肺动脉闭锁的男孩在2岁时接受了布莱洛克 - 陶西格分流术。9年后,他出现了短暂性失语。头颅计算机断层扫描(CT扫描)显示有一个与脑脓肿相符的结构。男孩意识清醒,未发现神经功能缺损。初始治疗包括氨苄西林、妥布霉素和甲硝唑,12天后出现急性偏瘫。从脑脓肿中抽出30毫升脓液,男孩的病情显著改善。细菌学检查发现米勒链球菌,并持续抗生素治疗六周。治疗期间及治疗后的系列CT扫描显示脑脓肿消失。该病例表明,在患有青紫型心脏病的患者进行分流手术后,右向左分流以及由此导致的慢性氧饱和度降低和红细胞增多症仍然存在,这些都是局灶性脑软化、脑炎和脑脓肿的促发因素。对于神经症状持续时间短且脓肿直径小于4厘米的情况,不进行完全切除而采用抗生素治疗可能消除感染。