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儿科急症中的急性酒精中毒。

Acute Alcohol Intoxication in Pediatric Emergencies.

机构信息

From the Pediatric Emergency Department, General University Hospital Gregorio Marañón, Madrid, Spain.

出版信息

Pediatr Emerg Care. 2022 Sep 1;38(9):e1523-e1528. doi: 10.1097/PEC.0000000000002808. Epub 2022 Jul 24.

Abstract

INTRODUCTION

Alcohol intoxication in pediatrics is a growing problem in our environment. The objectives of this study are to define the prevalence of acute alcohol intoxication in the pediatric emergency department (PED) and to describe the associated symptoms and their relationship with potential risk factors.

METHODS AND MATERIAL

This cross-sectional study includes patients younger than 16 years with a diagnosis of acute alcohol intoxication between March 2010 and October 2018 in the PED of a tertiary hospital. Patients with concomitant intoxication by other substances were excluded. The association between qualitative variables was determined using the χ 2 or Fisher exact test and quantitative with the Student t , Mann-Whitney U test, and simple linear regression.

RESULTS

There were 136 episodes of alcohol intoxication, which represents a prevalence of 24.1/100,000 emergencies. After excluding 10 patients because of positive screening for other drugs, 126 patients with a mean age of 14.5 years (SD, 1.2 years) were included, 57.9% of whom were women. A total of 25.4% of the patients were younger than 14 years. Ethanolemia was determined in 88.9%, and its mean concentration was 195.7 mg/dL (SD, 56.5 mg/dL), with potentially serious levels (>300 mg/dL) being found in 3.6% of the patients. A relationship was found between the Glasgow Coma Scale score and ethanolemia ( B = -12.7; 95% confidence interval, -8.1 to -17.4; P < 0.001), as well as with potassium ( B = -31, 9; 95% confidence interval, -6.6 to -57.3; P = 0.014). No patient had seizures or hypoglycemia. A total of 10.3% of the patients required admission.

CONCLUSIONS

Alcohol intoxication is a rare consultation reason in the PED. They usually present with mild and self-limited symptoms, being the decrease in the level of consciousness and hypokalemia the most frequent symptom and analytical alteration.

摘要

简介

儿科中的酒精中毒是我们环境中日益严重的问题。本研究的目的是确定儿科急诊部(PED)中急性酒精中毒的患病率,并描述相关症状及其与潜在危险因素的关系。

方法和材料

这是一项横断面研究,纳入了 2010 年 3 月至 2018 年 10 月在一家三级医院 PED 就诊的年龄小于 16 岁且被诊断为急性酒精中毒的患者。排除同时存在其他物质中毒的患者。使用卡方检验或 Fisher 确切检验比较定性变量,使用学生 t 检验、Mann-Whitney U 检验和简单线性回归比较定量变量。

结果

共发生了 136 例酒精中毒,患病率为 24.1/100000 急诊就诊。排除了 10 例因其他药物筛查阳性的患者后,共纳入了 126 例平均年龄为 14.5 岁(标准差,1.2 岁)的患者,其中 57.9%为女性。25.4%的患者年龄小于 14 岁。88.9%的患者检测了乙醇浓度,平均浓度为 195.7 mg/dL(标准差,56.5 mg/dL),其中 3.6%的患者存在潜在严重水平(>300 mg/dL)。格拉斯哥昏迷评分与乙醇浓度之间存在关系( B = -12.7;95%置信区间,-8.1 至-17.4;P < 0.001),与钾之间也存在关系( B = -31,9;95%置信区间,-6.6 至-57.3;P = 0.014)。没有患者出现癫痫发作或低血糖。共 10.3%的患者需要住院治疗。

结论

酒精中毒是儿科急诊就诊的罕见原因。它们通常表现为轻度和自限性症状,最常见的症状和分析改变是意识水平下降和低钾血症。

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