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关于自愿、辅助或非自愿精神科治疗决策的算法评估

Algorithmic Assessments in Deciding on Voluntary, Assisted or Involuntary Psychiatric Treatment.

作者信息

Grobler Gerhard, Van Staden Werdie

机构信息

Department of Psychiatry, Faculty of Health Sciences, University of Pretoria, Pretoria 0002, South Africa.

Centre for Ethics and Philosophy of Health Sciences, Faculty of Health Sciences, University of Pretoria, Pretoria 0002, South Africa.

出版信息

Diagnostics (Basel). 2022 Jul 26;12(8):1806. doi: 10.3390/diagnostics12081806.

Abstract

The challenges in assessing whether psychiatric treatment should be provided on voluntary, assisted or involuntary legal bases prompted the development of an assessment algorithm that may aid clinicians. It comprises a part that assesses the incapacity to provide informed consent to treatment, care or rehabilitation. It also captures the patient’s willingness to receive these treatments, the risk posed to the patient’s health or safety, financial interests or reputation and risks of serious harm to self or others. By following various decision paths, the algorithm yields one of four legal states: a voluntary, assisted, or involuntary state or that the proposed intervention should be declined. This study examined the predictive validity and the reliability of this algorithm. It was applied 4052 times to 135 clinical case narratives by 294 research participants. The legal states yielded by the algorithm had high statistical significance when matched with the gold standard (Chi-squared = 6963; df = 12; p < 0.001). It was accurate in yielding the correct legal state for the voluntary, assisted, involuntary and decline categories in 94%, 92%, 88% and 86% of the clinical case narratives, respectively. For internal reliability, a correspondence model accounted for 99.8% of the variance by which the decision paths clustered together fittingly with each of the legal states. Inter-rater reliability testing showed a moderate degree of agreement among participants on the suitable legal state (Krippendorff’s alpha = 0.66). These results suggest the algorithm is valid and reliable, which warrant a subsequent randomised controlled study to investigate whether it is more effective in clinical practice than standard assessments.

摘要

评估精神科治疗应基于自愿、协助还是非自愿法律基础所面临的挑战,促使人们开发出一种可能有助于临床医生的评估算法。该算法包括一部分,用于评估患者是否无能力对治疗、护理或康复给予知情同意。它还考量患者接受这些治疗的意愿、对患者健康或安全构成的风险、经济利益或声誉以及对自身或他人造成严重伤害的风险。通过遵循各种决策路径,该算法会得出四种法律状态之一:自愿、协助或非自愿状态,或者建议拒绝干预。本研究检验了该算法的预测效度和可靠性。294名研究参与者将其应用于135个临床病例叙述,共计4052次。当与金标准匹配时,该算法得出的法律状态具有高度统计学意义(卡方 = 6963;自由度 = 12;p < 0.001)。在临床病例叙述中,该算法分别在94%、92%、88%和86%的情况下准确得出自愿、协助、非自愿和拒绝类别的正确法律状态。对于内部可靠性,一个对应模型解释了决策路径与每种法律状态恰当聚类的99.8%的方差。评分者间信度测试表明,参与者在合适的法律状态上有中等程度的一致性(克里彭多夫阿尔法系数 = 0.66)。这些结果表明该算法有效且可靠,这值得后续进行随机对照研究,以调查其在临床实践中是否比标准评估更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e1e/9330761/cb618e5f0003/diagnostics-12-01806-g001.jpg

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