Department of Radiology, Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital), Zhuhai, China.
J Int Med Res. 2022 Jul;50(7):3000605221112201. doi: 10.1177/03000605221112201.
Solitary fibrous tumors (SFTs) are commonly seen in the pleura. SFT involvement of the vulva is rare, and clinical diagnosis is mainly based on histopathological and immunohistochemical analyses. We herein describe the imaging features of a 69-year-old woman with an SFT of the vulva. The SFT was hypointense on T1-weighted images, similar to muscle; however, it showed inhomogeneous hyperintensity predominantly on fat-suppressed T2-weighted images. An area of low signal intensity was evident on T2-weighted images, and the tumor showed progressive enhancement in delayed phases. The tumor also displayed heterogeneous and prolonged, persistent enhancement, and serpentine vessels were present in the peritumoral area as signal voids. Pathological examination confirmed that the lesion was an atypical SFT originating from the vulva, and it was composed of spindle cells and perivascular and stromal hyalinization. This case reveals the characteristic imaging findings of vulvar SFT and their association with the relevant pathological findings, thus contributing to the primary diagnosis and preoperative evaluation of this potentially aggressive tumor.
孤立性纤维瘤(SFT)常见于胸膜。外阴 SFT 罕见,临床诊断主要基于组织病理学和免疫组织化学分析。本文描述了 1 例 69 岁女性外阴 SFT 的影像学特征。SFT 在 T1 加权图像上呈低信号,类似于肌肉;然而,在脂肪抑制 T2 加权图像上呈不均匀高信号。T2 加权图像上可见低信号区域,肿瘤在延迟期呈进行性强化。肿瘤还表现出不均匀和持久的强化,肿瘤周围区域存在信号缺失的迂曲血管。病理检查证实病变为源自外阴的非典型 SFT,由梭形细胞和血管周围及间质玻璃样变组成。该病例揭示了外阴 SFT 的特征性影像学表现及其与相关病理表现的关系,有助于对这种潜在侵袭性肿瘤进行初步诊断和术前评估。