Department of Gynecology, Institut Clínic of Gynecology, Obstetrics and Neonatology, Hospital Clínic of Barcelona, University of Barcelona, Barcelona, Spain; Institut de Salut Global Barcelona - ISGlobal, Barcelona, Spain.
Institut de Salut Global Barcelona - ISGlobal, Barcelona, Spain; Department of Microbiology, Biomedical Diagnostic Center (CDB), Hospital Clínic of Barcelona, University of Barcelona, Barcelona, Spain.
Enferm Infecc Microbiol Clin (Engl Ed). 2022 Aug-Sep;40(7):377-380. doi: 10.1016/j.eimce.2021.03.008.
The aim of this study was to investigate the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in women with pelvic inflammatory disease (PID) and the usefulness and cost-effectiveness of a rapid molecular test for the diagnosis and clinical management of PID.
This observational study included 75 patients with mild-to-moderate PID (n=33), severe PID (n=29) and non-specific lower abdominal pain (NSAP) (n=13). CT/NG infections were analyzed using a standard and a rapid test. A cost analysis was carried out.
Samples of 19 patients (25.3%) were CT/NG positive. Concordance between rapid and standard tests was 100%. No significant differences were observed in the incidence of CT/NG in mild-to-moderate compared to severe PID. Costs differed according only to disease severity.
Rapid molecular tests could help with the diagnosis of PID in sexually active women in clinical settings in which a standard technique is not available.
本研究旨在调查盆腔炎（PID）患者中沙眼衣原体（CT）和淋病奈瑟菌（NG）的流行情况，以及快速分子检测在 PID 诊断和临床管理中的实用性和成本效益。
本观察性研究纳入了 75 例轻度至中度 PID（n=33）、重度 PID（n=29）和非特异性下腹痛（NSAP）（n=13）患者。使用标准和快速检测方法分析 CT/NG 感染。进行了成本分析。
19 名患者（25.3%）的样本 CT/NG 检测呈阳性。快速检测与标准检测之间的一致性为 100%。轻度至中度 PID 与重度 PID 相比，CT/NG 的发生率无显著差异。仅根据疾病严重程度，成本有所不同。
在无法使用标准技术的临床环境中，快速分子检测可帮助有性行为的女性诊断 PID。
