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计算机断层扫描提示通过将戊巴比妥钠肌肉注射到腹直肌进行自杀未遂。

A suicide attempt by intramuscular injection of pentobarbital sodium into rectus abdominis suggested by computed tomography.

作者信息

Nakayama Ryuichi, Sato Hiroki, Yama Naoya, Ogura Keishi, Kyan Ryoko, Hanazawa Tomoki, Yoshizawa Tomohiro, Miyamoto Masamune, Kamijo Yoshito, Mizuno Hirotoshi, Inamura Hirotoshi, Harada Keisuke, Uemura Shuji, Narimatsu Eichi

机构信息

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, 291, Minami 1-jo Nishi 16-chome, Chuo-ku, Sapporo, 060-8556, Japan.

Department of Diagnostic Radiology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.

出版信息

Forensic Sci Med Pathol. 2023 Jun;19(2):198-201. doi: 10.1007/s12024-022-00508-y. Epub 2022 Jul 30.

Abstract

Suicide attempts in humans due to injections of the veterinary drug pentobarbital sodium have been rarely reported. Herein, we present a case of a suicide attempt by intramuscular injection of pentobarbital sodium into the rectus abdominis muscle, which was suggested by computed tomography (CT). A 73-year-old man was brought to the emergency department with GCS 3 (E1V1M1) and an incised wound on the right side of the neck. A bottle of Somnopentyl (pentobarbital sodium, 64.8 mg/ml), a 20-ml empty syringe with an 18-mm needle, and no. 10 scalpel were present at the scene. At the emergency department, the patient was intubated and was admitted to the intensive care unit. A urine drug screen test by SIGNIFY ER was positive for benzodiazepines and barbiturates, and continuous veno-venous hemofiltration (CHF) was initiated. The route of drug administration was initially unknown; however, a CT scan revealed swelling of the left rectus abdominis muscle with a wound suggestive of a needle puncture, and the CT analysis suggested 38.16 ml as the maximum dose of pentobarbital sodium. On day 3, the patient's consciousness improved, and he was weaned off CHF and mechanical ventilation. There have been several reports of postmortem CT yielding information on the site of administration of intoxicants, but there have been none for surviving intoxicated patients. This is the first report of the usefulness of CT to identify the site of administration of the causative agent of intoxication while the patient is still alive.

摘要

因注射兽药戊巴比妥钠而导致人类自杀未遂的情况鲜有报道。在此,我们报告一例通过将戊巴比妥钠肌肉注射入腹直肌自杀未遂的病例,这一情况由计算机断层扫描(CT)显示。一名73岁男性被送至急诊科,格拉斯哥昏迷评分(GCS)为3分(E1V1M1),颈部右侧有一处切割伤。现场发现一瓶速眠新(戊巴比妥钠,64.8毫克/毫升)、一支配有18毫米针头的20毫升空注射器和一把10号手术刀。在急诊科,患者接受了气管插管并被收入重症监护病房。通过SIGNIFY ER进行的尿液药物筛查检测显示苯二氮䓬类和巴比妥类药物呈阳性,并启动了持续静脉-静脉血液滤过(CHF)。药物给药途径起初不明;然而,CT扫描显示左腹直肌肿胀并有一处提示针刺的伤口,CT分析提示戊巴比妥钠的最大剂量为38.16毫升。第3天,患者意识有所改善,停止了CHF和机械通气。已有数篇关于死后CT提供中毒剂给药部位信息的报道,但尚无关于中毒存活患者的此类报道。这是关于CT在患者仍存活时识别中毒致病剂给药部位有用性的首例报道。

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