Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Acta Otorrinolaringol Esp (Engl Ed). 2022 Jul-Aug;73(4):203-209. doi: 10.1016/j.otoeng.2021.03.004.
In the clinical assessment of chronic rhinosinusitis with nasal polyps (CRSwNP), evaluation of symptoms, nasoendoscopy findings and sinus computed tomography (CT) scan staging is employed in the management plan. Although prior studies have been done to assess the correlation of the three modalities in CRSwNP, such evaluation in patients with eosinophilic and non-eosinophilic types of CRSwNP requires further investigation. The aim of this study was to correlate the sinus CT scan staging to symptom and endoscopic scores in both types of CRSwNP.
Patients with CRSwNP were classified into 2 types, eosinophilic and non-eosinophilic. Both types were assessed by Sino-Nasal Outcome Test 22 (SNOT-22) symptom score, nasal endoscopy Lund Kennedy grading (LK) score and sinus CT Lund Mackay (LM) staging score. All three modalities were correlated.
Forty-four patients were recruited for this study. There was significant correlation between sinus CT and symptom scores in the eosinophilic (r=.51, p=.031) and the non-eosinophilic (r=.76, p<.001) types. There was no significant correlation between symptom and nasoendoscopic scores in the eosinophilic (r=.12, p=.641) and the non-eosinophilic (r=.22, p=.276) types. There was also no significant correlation between sinus CT and nasoendoscopic scores in the eosinophilic (r=.20, p=.418) and the non-eosinophilic (r=.14, p=.508) types.
Sinus CT staging correlates well with the symptom score for both the eosinophilic and the non-eosinophilic types of CRSwNP. The good correlation suggests both modalities are a reliable guide for their evaluation and management planning.
在慢性鼻-鼻窦炎伴鼻息肉（CRSwNP）的临床评估中，评估症状、鼻内镜检查结果和鼻窦计算机断层扫描（CT）分期都被纳入管理方案中。尽管先前已经有研究评估了这三种方式在 CRSwNP 中的相关性，但在嗜酸性和非嗜酸性 CRSwNP 患者中，这种评估需要进一步研究。本研究旨在评估 CT 扫描分期与这两种类型的 CRSwNP 的症状和内镜评分之间的相关性。
将 CRSwNP 患者分为嗜酸性和非嗜酸性两种类型。这两种类型均采用 Sino-Nasal Outcome Test 22（SNOT-22）症状评分、鼻内镜 Lund Kennedy 分级（LK）评分和鼻窦 CT Lund Mackay（LM）分期评分进行评估。对所有三种方式进行相关性分析。
本研究共纳入 44 例患者。在嗜酸性（r=.51，p=.031）和非嗜酸性（r=.76，p<.001）类型中，鼻窦 CT 与症状评分之间存在显著相关性。在嗜酸性（r=.12，p=.641）和非嗜酸性（r=.22，p=.276）类型中，症状与鼻内镜评分之间无显著相关性。在嗜酸性（r=.20，p=.418）和非嗜酸性（r=.14，p=.508）类型中，鼻窦 CT 与鼻内镜评分之间也无显著相关性。
鼻窦 CT 分期与嗜酸性和非嗜酸性 CRSwNP 的症状评分均具有良好的相关性。这种良好的相关性表明，这两种方式都是评估和管理计划的可靠指南。
