Sabin H I, Bentivoglio P, Symon L, Cheesman A D, Prasher D, Momma F
Acta Neurochir (Wien). 1987;85(3-4):110-6. doi: 10.1007/BF01456106.
Intra-operative electrocochleography (ECochG) was used in an attempt to monitor the action potential of the cochlear nerve during acoustic neuroma surgery in 14 patients with useful pre-operative hearing. Five patients had ECochG potentials preserved and yet only three could hear when tested audiometrically later. Of those losing the potentials intra-operatively all were subsequently deaf and the pattern of waveform loss allowed determination of the probable cause of hearing loss. Complete excision of the tumour was achieved in each case regardless of the ultimate effect on the AP as it was not felt justified to risk subsequent recurrence. In common with other studies one of the best prognostic factors for these preservation of hearing was found to be the size of the tumour.
对14例术前听力尚好的听神经瘤患者，术中采用耳蜗电图（ECochG）监测耳蜗神经动作电位。5例患者术中耳蜗电图电位得以保留，但之后听力测试时只有3例仍有听力。术中失去电位的患者术后均全聋，波形丢失模式有助于确定听力损失的可能原因。尽管术中耳蜗电图电位最终情况各异，但每例患者的肿瘤均实现了完整切除，因为人们认为冒后续复发的风险是不合理的。与其他研究一致，发现肿瘤大小是这些患者听力保留的最佳预后因素之一。
