School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Department of Urology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Curr Opin Urol. 2022 Sep 1;32(5):545-553. doi: 10.1097/MOU.0000000000001026.
Female sexual function after radical cystectomy is a crucial, but historically overlooked component of bladder cancer survivorship. This review focuses on recent studies, which have investigated pelvic health and sexual function after radical cystectomy. We discuss modifiable factors, which may contribute to decreased sexual function after radical cystectomy and techniques, which may lead to improved outcomes.
Sexual function is important to women and there is a significant desire (and unmet need) for more perioperative counseling and discussion regarding sexual function changes and quality of life impacts. Sexual function may be altered due to a combination of hormonal changes from ovarian removal, anatomic changes from vaginal alteration, and sensation changes due to damage to the neurovascular bundle. Techniques to preserve these structures have been developed.
Sexual function is an important component of survivorship and increasing attention is being focused on this area. Long term studies with objective measures are needed for to compare various techniques and ensure oncologic safety. Ovarian preservation, anterior vaginal wall preservation, and vaginal estrogen replacement should be carefully considered for most patients.
根治性膀胱切除术(radical cystectomy)后女性性功能是膀胱癌生存者的一个关键但历史上被忽视的组成部分。本综述重点介绍了最近研究,这些研究调查了根治性膀胱切除术后的盆腔健康和性功能。我们讨论了可能导致根治性膀胱切除术后性功能下降的可改变因素,以及可能导致改善结果的技术。
性功能对女性很重要,对于手术前后性功能变化和生活质量影响的咨询和讨论存在显著需求(但未得到满足)。性功能可能会因卵巢切除引起的激素变化、阴道改变引起的解剖变化以及神经血管束损伤引起的感觉变化而改变。已经开发了一些保留这些结构的技术。
性功能是生存的重要组成部分,越来越多的人关注这一领域。需要进行长期的研究,采用客观的测量方法,比较各种技术并确保肿瘤学安全性。对于大多数患者,应仔细考虑卵巢保留、前阴道壁保留和阴道雌激素替代。