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[新冠长期症状的频率、频谱和风险因素]

[Frequency, spectrum and risk factors of long COVID].

作者信息

Pink Isabell, Welte Tobias

机构信息

Klinik für Pneumologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

出版信息

Inn Med (Heidelb). 2022 Aug;63(8):813-818. doi: 10.1007/s00108-022-01370-4. Epub 2022 Jul 7.

Abstract

Between 10 and 20% of individuals infected with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) suffer from symptoms up to weeks after initial infection. The most frequently reported symptoms include fatigue, dyspnea, anosmia and ageusia, as well as headaches, joint pain, cough, cognitive impairment and impaired sleeping. After exclusion of other etiologies and symptom duration of more than 4 weeks after initial infection this is referred to as long COVID. In contrast to acute coronavirus disease 2019 (COVID-19), no specific risk factors have been identified as yet as being associated with the occurrence of this disease. Furthermore, there are varying hypotheses concerning the pathomechanism of long COVID. Dividing patients into groups is beneficial in the clinical context. Regardless of long COVID symptoms the risk of cardiovascular events is increased even 1 year after COVID-19.

摘要

感染严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)的个体中,10%至20%会在初次感染数周后出现症状。最常报告的症状包括疲劳、呼吸困难、嗅觉丧失和味觉丧失,以及头痛、关节疼痛、咳嗽、认知障碍和睡眠障碍。在排除其他病因且初次感染后症状持续超过4周后,这被称为“长新冠”。与2019年急性冠状病毒病(COVID-19)不同,目前尚未确定与这种疾病发生相关的特定风险因素。此外,关于“长新冠”的发病机制有多种假说。在临床环境中将患者分组是有益的。无论有无“长新冠”症状,即使在COVID-19感染1年后,心血管事件的风险也会增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99ad/9261882/c40807042ab0/108_2022_1370_Fig1_HTML.jpg

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