Bingman V P, Ioalè P, Casini G, Bagnoli P
Behav Brain Res. 1987 May;24(2):147-56. doi: 10.1016/0166-4328(87)90252-x.
Hippocampal-parahippocampal-ablated homing pigeons have been shown to suffer a retrograde loss of information used in the recognition of their home loft. Here we report that the range of retrograde deficits includes spatial reference memory in the form of information gained from repeated training sites that can be used to direct a homeward orientation response. Following 8 training releases from each of two sites, 28 of 42 homing pigeons underwent hippocampal-parahippocampal ablation. In the subsequent test releases from the two sites, untreated controls whose navigational map was rendered temporarily dysfunctional by an anosmic procedure showed no impairment in determining the home direction, indicating the successful retention and utilization of directionally useful information around the release sites. Hippocampal-ablated controls who were not rendered anosmic and thus had access to their navigational map also showed no impairment in determining the home direction, indicating no general impairment in initial orientation as a result of hippocampal ablation. In contrast, hippocampal-ablated pigeons whose navigational map was rendered temporarily dysfunctional failed to successfully orient homeward from the training sites, indicating impairment in the retention and/or implementation of directional information gathered at the release sites during training. The data reveal a spatial reference memory deficit involving pre-ablation acquired directional information in homing pigeons following hippocampal ablation.
已证明海马旁海马切除的归巢鸽在识别其鸽舍时会出现逆行性信息丧失。在此我们报告，逆行性缺陷的范围包括空间参考记忆，其形式为从重复训练地点获得的信息，可用于引导归巢方向反应。在从两个地点各进行8次训练放飞后，42只归巢鸽中有28只接受了海马旁海马切除。在随后从这两个地点进行的测试放飞中，通过嗅觉缺失程序使其导航地图暂时功能失调的未处理对照组在确定归巢方向时没有受损，这表明在放飞地点周围成功保留并利用了方向有用信息。未进行嗅觉缺失处理从而能够使用其导航地图的海马切除对照组在确定归巢方向时也没有受损，这表明海马切除并未导致初始定向出现一般性损伤。相比之下，其导航地图暂时功能失调的海马切除鸽未能从训练地点成功归巢，这表明在训练期间在放飞地点收集的方向信息的保留和/或实施受到了损害。数据揭示了海马切除后归巢鸽存在涉及切除前获取的方向信息的空间参考记忆缺陷。
