Al-Jabbari Esraa, Shroff Neel, Khan Hasan, Falamaki Maryamnaz, Bhargava Peeyush
Department of Radiology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.
Radiol Case Rep. 2022 Aug 4;17(10):3731-3734. doi: 10.1016/j.radcr.2022.06.083. eCollection 2022 Oct.
Gynecological malignancies including primary cervical cancers are frequently treated with chemotherapy and radiation. Fistulas affecting the gynecological organs and surrounding cavities are a known consequence of radiotherapy due to focal necrosis of the regional mucosa. In this report, we will demonstrate a rare case of a posterior vaginal wall rupture with resulting fistulization into the peritoneal cavity in a 50-year-old female patient with squamous cell carcinoma of the cervix status postchemoradiotherapy. Magnetic resonance imaging (MRI) showed a discontinuity in the posterior vaginal wall near the fornix with extravasation of ultrasound gel used as contrast into the intraperitoneal compartment. Patient later presented with peritonitis like signs and symptoms and was treated successfully with antibiotics. Vaginal gel should be used with caution in patients with prior history of radiation due to the possibility of vaginal rupture which may lead to peritoneal vaginal fistula and contrast extravasation.
包括原发性宫颈癌在内的妇科恶性肿瘤常采用化疗和放疗进行治疗。由于局部黏膜坏死,影响妇科器官和周围腔隙的瘘管是放疗的一个已知后果。在本报告中,我们将展示一例罕见病例,一名50岁接受过放化疗的宫颈鳞状细胞癌女性患者,出现阴道后壁破裂并形成通向腹腔的瘘管。磁共振成像(MRI)显示穹窿附近阴道后壁连续性中断,用作造影剂的超声凝胶渗入腹腔。患者后来出现类似腹膜炎的体征和症状,并通过抗生素治疗成功治愈。由于既往有放疗史的患者可能发生阴道破裂,进而导致腹膜阴道瘘和造影剂外渗,因此应谨慎使用阴道凝胶。