Suppr超能文献

[舌鳞状细胞癌外科治疗专家共识]

[Expert consensus on surgical treatment of tongue squamous cell carcinoma].

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 2022 Aug 9;57(8):836-848. doi: 10.3760/cma.j.cn112144-20220530-00289.

Abstract

The annual incidence of oral cancer in the world is more than 300 000, and the five-year survival rate is 50%~60%. Every year, 145 400 people died due to tongue cancer, of which tongue cancer accounts for nearly 40%. Although tongue cancer has tumor heterogeneity and individual differences in prognosis, surgery is still the first choice for the treatment of tongue cancer. The effect of tongue cancer surgery can directly determine the survival time of patients. The defect caused by tongue cancer surgery seriously affects the patients' physical functions such as appearance, language, chewing and swallowing. The surgical treatment of tongue cancer with functional reconstruction can improve the quality of life of patients. In the past few decades, genomics has enhanced understanding of tongue cancer. The preclinical tumor model preserves the tumor heterogeneity, which has a great application prospect in the discovery of tumor biomarkers and the clinical translation of drugs. Many advances have been made in the diagnosis and treatment of tongue cancer, but there are still many controversies in clinical practice. Therefore, this expert consensus summarizes the progress and controversial hot spots of surgical diagnosis and treatment of tongue cancer, mainly including preoperative diagnosis and evaluation, surgical treatment points and postoperative functional rehabilitation.

摘要

世界范围内口腔癌的年发病率超过30万,五年生存率为50%至60%。每年有145400人死于舌癌,其中舌癌占近40%。尽管舌癌存在肿瘤异质性且预后存在个体差异,但手术仍是舌癌治疗的首选。舌癌手术效果直接决定患者的生存时间。舌癌手术造成的缺损严重影响患者的外观、语言、咀嚼和吞咽等身体功能。功能性重建的舌癌手术治疗可提高患者生活质量。在过去几十年中,基因组学增进了对舌癌的认识。临床前肿瘤模型保留了肿瘤异质性,在肿瘤生物标志物发现及药物临床转化方面具有巨大应用前景。舌癌的诊断和治疗虽已取得诸多进展,但临床实践中仍存在许多争议。因此,本专家共识总结了舌癌外科诊疗的进展及争议热点,主要包括术前诊断与评估、手术治疗要点及术后功能康复。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验